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Target
Adenosine receptor A3
Ligand
BDBM50221701
Substrate
n/a
Meas. Tech.
ChEMBL_449697 (CHEMBL898802)
Ki
>1000±n/a nM
Citation
 Drabczynska, A; Müller, CE; Schiedel, A; Schumacher, B; Karolak-Wojciechowska, J; Fruzinski, A; Zobnina, W; Yuzlenko, O; Kiec-Kononowicz, K Phenylethyl-substituted pyrimido[2,1-f]purinediones and related compounds: structure-activity relationships as adenosine A(1) and A(2A) receptor ligands. Bioorg Med Chem 15:6956-74 (2007) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50221701
Synonyms:
9-(3,4-dimethoxyphenethyl)-1,3-dipropyl-6,7,8,9-tetrahydropyrimido[1,2-a]purine-2,4(1H,3H)-dione | CHEMBL391717
Type:
Small organic molecule
Emp. Form.:
C24H33N5O4
Mol. Mass.:
455.5499
SMILES:
CCCn1c2nc3N(CCc4ccc(OC)c(OC)c4)CCCn3c2c(=O)n(CCC)c1=O
Structure:
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