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Target
Monoglyceride lipase
Ligand
BDBM50274152
Substrate
n/a
Meas. Tech.
ChEMBL_537181 (CHEMBL992557)
Ki
21800±n/a nM
Citation
 Magrioti, V; Naxakis, G; Hadjipavlou-Litina, D; Makriyannis, A; Kokotos, G A novel monoacylglycerol lipase inhibitor with analgesic and anti-inflammatory activity. Bioorg Med Chem Lett 18:5424-7 (2008) [PubMed]  Article 
Target
Name:
Monoglyceride lipase
Synonyms:
MAGL | MGLL_RAT | Mgl2 | Mgll | Monoacylglycerol lipase | Monoglyceride lipase | Monoglyceride lipase (MGL)
Type:
Enzyme
Mol. Mass.:
33505.38
Organism:
Rattus norvegicus (Rat)
Description:
Q8R431
Residue:
303
Sequence:
MPEASSPRRTPQNVPYQDLPHLVNADGQYLFCRYWKPSGTPKALIFVSHGAGEHCGRYDELAQMLKRLDMLVFAHDHVGHGQSEGERMVVSDFQVFVRDLLQHVNTVQKDYPEVPVFLLGHSMGGAISILAAAERPTHFSGMILISPLILANPESASTLKVLAAKLLNFVLPNISLGRIDSSVLSRNKSEVDLYNSDPLICHAGVKVCFGIQLLNAVSRVERAMPRLTLPFLLLQGSADRLCDSKGAYLLMESSPSQDKTLKMYEGAYHVLHKELPEVTNSVLHEINTWVSHRIAVAGARCLP
  
Inhibitor
Name:
BDBM50274152
Synonyms:
(2S,9Z)-octadec-9-ene-1,2-diamine dihydrochloride | CHEMBL500707
Type:
Small organic molecule
Emp. Form.:
C18H38N2
Mol. Mass.:
282.5077
SMILES:
CCCCCCCC\C=C/CCCCCC[C@H](N)CN |r|
Structure:
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