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Target
Thromboxane A2 receptor
Ligand
BDBM50047274
Substrate
n/a
Meas. Tech.
ChEMBL_210268 (CHEMBL809292)
Kd
4±n/a nM
Citation
 Das, J; Reid, JA; Harris, DN; Goldenberg, H; Michel, IM; Monshizadegan, H; Webb, ML Thoromboxane A2/endoperoxide receptor antagonists: 1,3-Dioxane and 1,3-dioxolane analogs Bioorg Med Chem Lett 3:1271-1276 (1993)    Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50047274
Synonyms:
3-{2-[3-(4-Pentylcarbamoyl-oxazol-2-yl)-7-oxa-bicyclo[2.2.1]hept-2-ylmethyl]-phenyl}-propionic acid | BMS-180291 | CHEMBL283100
Type:
Small organic molecule
Emp. Form.:
C25H32N2O5
Mol. Mass.:
440.532
SMILES:
CCCCCNC(=O)c1coc(n1)C1C2CCC(O2)C1Cc1ccccc1CCC(O)=O |TLB:20:19:18:15.16,THB:11:13:18:15.16|
Structure:
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