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Target
Serine hydrolase RBBP9
Ligand
BDBM50314724
Substrate
n/a
Meas. Tech.
ChEMBL_625879 (CHEMBL1114312)
IC50
9200±n/a nM
Citation
 Bachovchin, DA; Wolfe, MR; Masuda, K; Brown, SJ; Spicer, TP; Fernandez-Vega, V; Chase, P; Hodder, PS; Rosen, H; Cravatt, BF Oxime esters as selective, covalent inhibitors of the serine hydrolase retinoblastoma-binding protein 9 (RBBP9). Bioorg Med Chem Lett 20:2254-8 (2010) [PubMed]  Article 
Target
Name:
Serine hydrolase RBBP9
Synonyms:
BOG | Putative hydrolase RBBP9 | RBBP10 | RBBP9 | RBBP9_HUMAN
Type:
PROTEIN
Mol. Mass.:
20998.17
Organism:
Homo sapiens (Human)
Description:
ChEMBL_625879
Residue:
186
Sequence:
MASPSKAVIVPGNGGGDVTTHGWYGWVKKELEKIPGFQCLAKNMPDPITARESIWLPFMETELHCDEKTIIIGHSSGAIAAMRYAETHRVYAIVLVSAYTSDLGDENERASGYFTRPWQWEKIKANCPYIVQFGSTDDPFLPWKEQQEVADRLETKLHKFTDCGHFQNTEFHELITVVKSLLKVPA
  
Inhibitor
Name:
BDBM50314724
Synonyms:
1-(thiazol-2-yl)ethanone O-4-methoxybenzoyl oxime | CHEMBL1092114
Type:
Small organic molecule
Emp. Form.:
C13H12N2O3S
Mol. Mass.:
276.311
SMILES:
COc1ccc(cc1)C(=O)O\N=C(/C)c1nccs1
Structure:
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