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Target
High affinity choline transporter 1
Ligand
BDBM50047005
Substrate
n/a
Meas. Tech.
ChEMBL_644789 (CHEMBL1211032)
Ki
210377.84±n/a nM
Citation
 Geldenhuys, WJ; Allen, DD; Lockman, PR 3-D-QSAR and docking studies on the neuronal choline transporter. Bioorg Med Chem Lett 20:4870-7 (2010) [PubMed]  Article 
Target
Name:
High affinity choline transporter 1
Synonyms:
Choline transporter | Cht1 | SC5A7_MOUSE | Slc5a7
Type:
PROTEIN
Mol. Mass.:
63358.06
Organism:
Mus musculus
Description:
ChEMBL_644789
Residue:
580
Sequence:
MSFHVEGLVAIILFYLLIFLVGIWAAWKTKNSGNPEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYGPGCGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDVNISVIVSALIAILYTLVGGLYSVAYTDVVQLFCIFIGLWISVPFALSHPAVTDIGFTAVHAKYQSPWLGTIESVEVYTWLDNFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMALPAICIGAIGASTDWNQTAYGYPDPKTKEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVLVFGASATAMALLTKTVYGLWYLSSDLVYIIIFPQLLCVLFIKGTNTYGAVAGYIFGLFLRITGGEPYLYLQPLIFYPGYYSDKNGIYNQRFPFKTLSMVTSFFTNICVSYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVRNENIKLNELAPVKPRQSLTLSSTFTNKEALLDVDSSPEGSGTEDNLQ
  
Inhibitor
Name:
BDBM50047005
Synonyms:
1-Aza-bicyclo[2.2.2]octan-3-ol | 1-Aza-bicyclo[2.2.2]octan-3-ol (3-quinuclidinol) | 3-hydroxy-1-azoniabicyclo[2.2.2]octane | CHEMBL276310
Type:
Small organic molecule
Emp. Form.:
C7H13NO
Mol. Mass.:
127.1842
SMILES:
OC1CN2CCC1CC2 |THB:0:1:7.8:5.4,(6.92,.2,;7.84,-.7,;6.97,-1.64,;7.02,-3.14,;8.8,-4.11,;9.62,-2.84,;7.9,-1.89,;6.04,-2.81,;5.27,-4.16,)|
Structure:
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