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Target
D-amino-acid oxidase
Ligand
BDBM31156
Substrate
n/a
Meas. Tech.
ChEMBL_769923 (CHEMBL1832107)
Kd
2.5±n/a nM
Citation
 Lange, JH; Venhorst, J; van Dongen, MJ; Frankena, J; Bassissi, F; de Bruin, NM; den Besten, C; de Beer, SB; Oostenbrink, C; Markova, N; Kruse, CG Biophysical and physicochemical methods differentiate highly ligand-efficient human D-amino acid oxidase inhibitors. Eur J Med Chem 46:4808-19 (2011) [PubMed]  Article 
Target
Name:
D-amino-acid oxidase
Synonyms:
D-amino-acid oxidase (DAAO) | DAAO | DAMOX | DAO | OXDA_HUMAN
Type:
Homodimer
Mol. Mass.:
39476.06
Organism:
Homo sapiens (Human)
Description:
P14920
Residue:
347
Sequence:
MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPNNPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPRELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVNCTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGGIFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGPSNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
  
Inhibitor
Name:
BDBM31156
Synonyms:
3-hydroxyquinolin-2(1H)-one, 10
Type:
Small organic molecule
Emp. Form.:
C9H6ClNO2
Mol. Mass.:
195.602
SMILES:
Oc1cc2c(Cl)cccc2[nH]c1=O
Structure:
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