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Target
Sodium- and chloride-dependent creatine transporter 1
Ligand
BDBM50147104
Substrate
n/a
Meas. Tech.
ChEBML_49277
Ki
45000±n/a nM
Citation
 Geldenhuys, WJ; Lockman, PR; McAfee, JH; Fitzpatrick, KT; Van der Schyf, CJ; Allen, DD Molecular modeling studies on the active binding site of the blood-brain barrier choline transporter. Bioorg Med Chem Lett 14:3085-92 (2004) [PubMed]  Article 
Target
Name:
Sodium- and chloride-dependent creatine transporter 1
Synonyms:
CHOT1 | CT1 | Creatine transporter | Creatine transporter 1 | SC6A8_RAT | Slc6a8 | Sodium- and chloride-dependent creatine transporter 1 | Solute carrier family 6 member 8
Type:
PROTEIN
Mol. Mass.:
70632.63
Organism:
Rattus norvegicus
Description:
ChEMBL_49276
Residue:
635
Sequence:
MAKKSAENGIYSVSGDEKKGPLIVSGPDGAPSKGDGPAGLGAPSSRLAVPPRETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSTGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMATEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVCMGIFIFNVVYYKPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQPIWGLHHLEYRAQDADVRGLTTLTPVSESSKVVVVESVM
  
Inhibitor
Name:
BDBM50147104
Synonyms:
3-(1-Methyl-pyrrolidin-2-yl)-1-octyl-piperidine | CHEMBL105667
Type:
Small organic molecule
Emp. Form.:
C18H36N2
Mol. Mass.:
280.4918
SMILES:
CCCCCCCCN1CCCC(C1)C1CCCN1C
Structure:
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