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Target
Tyrosine-protein phosphatase 1
Ligand
BDBM50143425
Substrate
n/a
Meas. Tech.
ChEBML_217570
IC50
30000±n/a nM
Citation
 Shrestha, S; Shim, YS; Kim, KC; Lee, KH; Cho, H Evans Blue and other dyes as protein tyrosine phosphatase inhibitors. Bioorg Med Chem Lett 14:1923-6 (2004) [PubMed]  Article 
Target
Name:
Tyrosine-protein phosphatase 1
Synonyms:
PTP1 | PTP1_YEAST | Protein-tyrosine phosphatase 1
Type:
PROTEIN
Mol. Mass.:
38875.77
Organism:
Saccharomyces cerevisiae
Description:
ChEMBL_217570
Residue:
335
Sequence:
MAAAPWYIRQRDTDLLGKFKFIQNQEDGRLREATNGTVNSRWSLGVSIEPRNDARNRYVNIMPYERNRVHLKTLSGNDYINASYVKVNVPGQSIEPGYYIATQGPTRKTWDQFWQMCYHNCPLDNIVIVMVTPLVEYNREKCYQYWPRGGVDDTVRIASKWESPGGANDMTQFPSDLKIEFVNVHKVKDYYTVTDIKLTPTDPLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNSRGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITERSRHSDRATEEYTRDLIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKYLNSLSVNQ
  
Inhibitor
Name:
BDBM50143425
Synonyms:
5-{1-[3-Carboxy-4-oxo-cyclohexa-2,5-dien-(E)-ylidene]-ethyl}-2-hydroxy-benzoic acid | CHEMBL175241
Type:
Small organic molecule
Emp. Form.:
C16H12O6
Mol. Mass.:
300.2629
SMILES:
C\C(=C1\C=CC(=O)C(=C1)C(O)=O)c1ccc(O)c(c1)C(O)=O |c:3,7|
Structure:
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