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Target
Deoxycytidine kinase
Ligand
BDBM50421873
Substrate
n/a
Meas. Tech.
ChEMBL_53732 (CHEMBL663658)
Ki
4600000±n/a nM
Citation
 Palomino, E; Meltsner, BR; Kessel, D; Horwitz, JP Synthesis and in vitro evaluation of some modified 4-thiopyrimidine nucleosides for prevention or reversal of AIDS-associated neurological disorders. J Med Chem 33:258-63 (1990) [PubMed]  Article 
Target
Name:
Deoxycytidine kinase
Synonyms:
DCK | DCK_HUMAN
Type:
PROTEIN
Mol. Mass.:
30510.65
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1437135
Residue:
260
Sequence:
MATPPKRSCPSFSASSEGTRIKKISIEGNIAAGKSTFVNILKQLCEDWEVVPEPVARWCNVQSTQDEFEELTMSQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL
  
Inhibitor
Name:
BDBM50421873
Synonyms:
CHEMBL2115278
Type:
Small organic molecule
Emp. Form.:
C9H11N3O3
Mol. Mass.:
209.2019
SMILES:
Nc1ccn([C@@H]2O[C@H](CO)C=C2)c(=O)n1 |r,c:10|
Structure:
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