Reaction Details Report a problem with these data
Target
Metabotropic glutamate receptor 4
Ligand
BDBM50053588
Substrate
n/a
Meas. Tech.
ChEMBL_106687 (CHEMBL714668)
Ki
838000±n/a nM
Citation
 Bertrand, HO; Bessis, AS; Pin, JP; Acher, FC Common and selective molecular determinants involved in metabotopic glutamate receptor agonist activity. J Med Chem 45:3171-83 (2002) [PubMed]  Article 
Target
Name:
Metabotropic glutamate receptor 4
Synonyms:
GPRC1D | GRM4 | GRM4_HUMAN | Glutamate receptor, metabotropic 4 | MGLUR4 | Metabotropic glutamate receptor 4 | Metabotropic glutamate receptor 4 (mGlu4) | Metabotropic glutamate receptor 4 (mGluR4) | metabotropic glutamate 4
Type:
Protein
Mol. Mass.:
101899.95
Organism:
Homo sapiens (Human)
Description:
Q14833
Residue:
912
Sequence:
MPGKRGLGWWWARLPLCLLLSLYGPWMPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGRGSEGKPCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSLTFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYASTAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQKSREDGGVCIAQSVKIPREPKAGEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKIAPVLHLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNIWFAEFWEDNFHCKLSRHALKKGSHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNDSAEYKVIGSWTDHLHLRIERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCWHCEPCTGYQYQVDRYTCKTCPYDMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIAATLFVVITFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMPKVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALATKQTYVTYTNHAI
  
Inhibitor
Name:
BDBM50053588
Synonyms:
(S)-4-(amino(carboxy)methyl)benzoic acid | (S)-4-carboxyphenylglycine | 4-((S)-Amino-carboxy-methyl)-benzoic acid | 4-(Amino-carboxy-methyl)-benzoic acid | CHEMBL94990 | S-4-Carboxyphenylglycine
Type:
Small organic molecule
Emp. Form.:
C9H9NO4
Mol. Mass.:
195.1721
SMILES:
N[C@H](C(O)=O)c1ccc(cc1)C(O)=O |r|
Structure:
Search PDB for entries with ligand similarity: