Reaction Details
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Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
Ligand
BDBM50090508
Substrate
n/a
Meas. Tech.
ChEMBL_197997 (CHEMBL798975)
IC50
>1000000±n/a nM
Citation
McCluskey, A; Sim, AT; Sakoff, JA Serine-threonine protein phosphatase inhibitors: development of potential therapeutic strategies. J Med Chem 45:1151-75 (2002) [PubMed] Article More Info.:
Target
Name:
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
Synonyms:
PP1G_HUMAN | PPP1CC | Serine/threonine protein phosphatase PP1-gamma catalytic subunit
Type:
PROTEIN
Mol. Mass.:
36983.39
Organism:
Homo sapiens (Human)
Description:
ChEMBL_473188
Residue:
323
Sequence:
MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKKPNATRPVTPPRGMITKQAKK
Inhibitor
Name:
BDBM50090508
Synonyms:
(1R,2S,6R,7S)-5-Methoxy-4,10-dioxa-tricyclo[5.2.1.0*2,6*]decan-3-one | CHEMBL298459
Type:
Small organic molecule
Emp. Form.:
C9H12O4
Mol. Mass.:
184.1892
SMILES:
COC1OC(=O)[C@@H]2[C@H]3CC[C@H](O3)[C@H]12
Structure:
