Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50181464
Substrate
n/a
Meas. Tech.
ChEMBL_330571 (CHEMBL871146)
Ki
>8000±n/a nM
Citation
 Muccioli, GG; Wouters, J; Charlier, C; Scriba, GK; Pizza, T; Di Pace, P; De Martino, P; Poppitz, W; Poupaert, JH; Lambert, DM Synthesis and activity of 1,3,5-triphenylimidazolidine-2,4-diones and 1,3,5-triphenyl-2-thioxoimidazolidin-4-ones: characterization of new CB1 cannabinoid receptor inverse agonists/antagonists. J Med Chem 49:872-82 (2006) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50181464
Synonyms:
1,3,5-triphenyl-2-thioxoimidazolidin-4-one | CHEMBL383249
Type:
Small organic molecule
Emp. Form.:
C21H16N2OS
Mol. Mass.:
344.43
SMILES:
Oc1c(-c2ccccc2)n(-c2ccccc2)c(=S)n1-c1ccccc1
Structure:
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