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Target
Dehydrogenase/reductase SDR family member 9
Ligand
BDBM50213553
Substrate
n/a
Meas. Tech.
ChEMBL_447932 (CHEMBL898183)
IC50
>1000000±n/a nM
Citation
 Harrak, Y; Rosell, G; Daidone, G; Plescia, S; Schillaci, D; Pujol, MD Synthesis and biological activity of new anti-inflammatory compounds containing the 1,4-benzodioxine and/or pyrrole system. Bioorg Med Chem 15:4876-90 (2007) [PubMed]  Article 
Target
Name:
Dehydrogenase/reductase SDR family member 9
Synonyms:
3-alpha hydroxysteroid dehydrogenase | 3-alpha-HSD | DHRS9_RAT | Dhrs9 | Short-chain dehydrogenase/reductase retSDR8 | eRolDH
Type:
PROTEIN
Mol. Mass.:
35223.09
Organism:
Rattus norvegicus
Description:
ChEMBL_447932
Residue:
319
Sequence:
MLLWVLALLFLCAFLWNYKGQLKIADIADKYIFITGCDSGFGNLAARTFDRKGFRVIAACLTESGSEALKAKTSERLHTVLLDVTNPENVKETAQWVKSHVGEKGLWGLINNAGVLGVLAPTDWLTVDDYREPIEVNLFGLINVTLNMLPLVKKARGRVINVSSIGGRLAFGGGGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLFKTGLADPIKTTEKKLAIWKHLSPDIKQQYGEGYIEKSLHRLKSSTSSVNLDLSLVVECMDHALTSLFPKTRYTAGKDAKTFWIPLSHMPAALQDFLLLKEKVELANPQAV
  
Inhibitor
Name:
BDBM50213553
Synonyms:
(S)-2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)propanoic acid | CHEMBL236433
Type:
Small organic molecule
Emp. Form.:
C11H12O4
Mol. Mass.:
208.2106
SMILES:
C[C@H](C(O)=O)c1ccc2OCCOc2c1
Structure:
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