Reaction Details Report a problem with these data
Target
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
Ligand
BDBM50299724
Substrate
n/a
Meas. Tech.
ChEMBL_588696 (CHEMBL1059305)
Ki
17±n/a nM
Citation
 Berardi, F; Abate, C; Ferorelli, S; Uricchio, V; Colabufo, NA; Niso, M; Perrone, R Exploring the importance of piperazine N-atoms for sigma(2) receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28). J Med Chem 52:7817-28 (2009) [PubMed]  Article 
Target
Name:
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
Synonyms:
EBP | EBP_CAVPO
Type:
PROTEIN
Mol. Mass.:
26684.52
Organism:
Cavia porcellus
Description:
ChEMBL_203193
Residue:
229
Sequence:
MATTSTGPLHPYWPRHLRLDHFVPNDLSAWYIVTVLFTVFGALVVTMWLLSSRASVVPLGTWRRLSVCWFAVCAFVHLVIEGWFVLYQKAILGDQAFLSQLWKEYAKGDSRYIIEDNFIICMESITVVLWGPLSLWAVIAFLRQHPSRYVLQFVISLGQIYGDLLYFLTEYRDGFQHGEMGHPIYFWFYFFFMNVLWLVIPGVLFFDSVKQFYGAQNALDTKVMKSKGK
  
Inhibitor
Name:
BDBM50299724
Synonyms:
1,4-dicyclohexylpiperazine | CHEMBL573703
Type:
Small organic molecule
Emp. Form.:
C16H30N2
Mol. Mass.:
250.4228
SMILES:
C1CCC(CC1)N1CCN(CC1)C1CCCCC1
Structure:
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