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Target
Serine racemase
Ligand
BDBM50129194
Substrate
n/a
Meas. Tech.
ChEMBL_594814 (CHEMBL1042553)
Ki
1900000±n/a nM
Citation
 Hoffman, HE; Jirásková, J; Cígler, P; Sanda, M; Schraml, J; Konvalinka, J Hydroxamic acids as a novel family of serine racemase inhibitors: mechanistic analysis reveals different modes of interaction with the pyridoxal-5'-phosphate cofactor. J Med Chem 52:6032-41 (2009) [PubMed]  Article 
Target
Name:
Serine racemase
Synonyms:
D-serine ammonia-lyase | D-serine dehydratase | L-serine ammonia-lyase | L-serine dehydratase | SRR_MOUSE | Srr
Type:
PROTEIN
Mol. Mass.:
36355.92
Organism:
Mus musculus
Description:
ChEMBL_1441161
Residue:
339
Sequence:
MCAQYCISFADVEKAHINIQDSIHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTPEEKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYCDPSDESREKVTQRIMQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMVAGIAITIKALKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWGRMKLLIEPTAGVALAAVLSQHFQTVSPEVKNVCIVLSGGNVDLTSLNWVGQAERPAPYQTVSV
  
Inhibitor
Name:
BDBM50129194
Synonyms:
(2S)-2-amino-4-(hydroxyamino)-4-oxobutanoic acidN(4)-hydroxy-L-asparagine | CHEMBL63902 | L-Asparaginsaeure-4-hydroxyamid | L-aspartic acid beta-hydroxamate | beta-L-Aspartylhydroxamate | beta-L-aspartylhydroxamic acid | beta-aspartohydroxamic acid
Type:
Small organic molecule
Emp. Form.:
C4H8N2O4
Mol. Mass.:
148.1173
SMILES:
N[C@@H](CC(=O)NO)C(O)=O
Structure:
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