Compile Data Set for Download or QSAR
maximum 50k data
Found 21 with Last Name = 'sanda' and Initial = 'm'
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50189917((R,S)-5-(3-amino-3-carboxy-propylsulfanyl)-pentano...)
Affinity DataKi:  12nMAssay Description:Binding affinity to human recombinant BHMT expressed in Escherichia coli using variable levels of betaine substrate by Dixon plotMore data for this Ligand-Target Pair
TargetSerine racemase(Mus musculus)
Institute Of Organic Chemistry And Biochemistry Of The Ascr

Curated by ChEMBL
LigandPNGBDBM50378533(CHEMBL568192)
Affinity DataKi:  4.30E+4nMAssay Description:Inhibition of mouse recombinant serine racemase transfected in bacterial expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine racemase(Mus musculus)
Institute Of Organic Chemistry And Biochemistry Of The Ascr

Curated by ChEMBL
LigandPNGBDBM14673(Fragment 3 | Malonic Acid | propanedioic acid)
Affinity DataKi:  7.10E+4nMAssay Description:Inhibition of mouse recombinant serine racemase transfected in bacterial expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine racemase(Mus musculus)
Institute Of Organic Chemistry And Biochemistry Of The Ascr

Curated by ChEMBL
LigandPNGBDBM50378532(CHEMBL569435)
Affinity DataKi:  4.17E+5nMAssay Description:Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine after 30 mins by Linewaver-bur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine racemase(Mus musculus)
Institute Of Organic Chemistry And Biochemistry Of The Ascr

Curated by ChEMBL
LigandPNGBDBM50378534(CHEMBL216796)
Affinity DataKi:  1.64E+6nMAssay Description:Inhibition of mouse recombinant serine racemase transfected in bacterial expression systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine racemase(Mus musculus)
Institute Of Organic Chemistry And Biochemistry Of The Ascr

Curated by ChEMBL
LigandPNGBDBM50129194((2S)-2-amino-4-(hydroxyamino)-4-oxobutanoic acidN(...)
Affinity DataKi:  1.90E+6nMAssay Description:Inhibition of mouse brain serine racemaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50268080((S)-5-(3-Amino-3-carboxypropylthio)-3,3-dimethylpe...)
Affinity DataIC50:  64nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50268079((RS)-5-(3-Amino-3-carboxypropylthio)-3,3-dimethylp...)
Affinity DataIC50:  84nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50189917((R,S)-5-(3-amino-3-carboxy-propylsulfanyl)-pentano...)
Affinity DataIC50:  138nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50268078((RS,RS)-5-(3-Amino-3-carboxypropylthio)-3-methylpe...)
Affinity DataIC50:  139nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50268032((RS)-5-(3-Amino-3-carboxypropylselanyl)pentanoic A...)
Affinity DataIC50:  649nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50268081((R)-5-(3-Amino-3-carboxypropylthio)-3,3-dimethylpe...)
Affinity DataIC50:  701nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50268055((RS)-2-Amino-4-{2-[(carboxymethyl)(methyl)amino]et...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50268031((RS)-2-Amino-4-[(2-carboxyethylthio)methylthio]but...)
Affinity DataIC50:  3.26E+3nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase(Acarus siro (Flour mite))
Academy of Sciences of The Czech Republic

LigandPNGBDBM23406((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Affinity DataIC50:  3.80E+3nMpH: 4.5Assay Description:α-Amylase activity was assayed with the chromogenic substrate RBB-starch. An enzyme aliquot was incubated (20 min, 26°C) with 0.3% RBB-starch in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine racemase(Mus musculus)
Institute Of Organic Chemistry And Biochemistry Of The Ascr

Curated by ChEMBL
LigandPNGBDBM50378531(CHEMBL566071)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine racemase(Mus musculus)
Institute Of Organic Chemistry And Biochemistry Of The Ascr

Curated by ChEMBL
LigandPNGBDBM50378530(CHEMBL566494)
Affinity DataIC50:  1.70E+5nMAssay Description:Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine racemase(Mus musculus)
Institute Of Organic Chemistry And Biochemistry Of The Ascr

Curated by ChEMBL
LigandPNGBDBM50378532(CHEMBL569435)
Affinity DataIC50:  3.70E+5nMAssay Description:Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine racemase(Mus musculus)
Institute Of Organic Chemistry And Biochemistry Of The Ascr

Curated by ChEMBL
LigandPNGBDBM50129194((2S)-2-amino-4-(hydroxyamino)-4-oxobutanoic acidN(...)
Affinity DataIC50:  1.30E+6nMAssay Description:Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine after 30 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50189917((R,S)-5-(3-amino-3-carboxy-propylsulfanyl)-pentano...)
Affinity DataKd:  280nMAssay Description:Binding affinity to human recombinant BHMT expressed in Escherichia coli by intrinsic tryptophan fluorescence studiesMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50268080((S)-5-(3-Amino-3-carboxypropylthio)-3,3-dimethylpe...)
Affinity DataKd:  83nMAssay Description:Binding affinity to human recombinant BHMT expressed in Escherichia coli by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed