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Target
Ras-related protein Rap-1A
Ligand
BDBM50310364
Substrate
n/a
Meas. Tech.
ChEMBL_676191 (CHEMBL1273311)
Kd
4000±n/a nM
Citation
 Ujihara, S; Oishi, T; Mouri, R; Tamate, R; Konoki, K; Matsumori, N; Murata, M; Oshima, Y; Sugiyama, N; Tomita, M; Ishihama, Y Detection of Rap1A as a yessotoxin binding protein from blood cell membranes. Bioorg Med Chem Lett 20:6443-6 (2010) [PubMed]  Article 
Target
Name:
Ras-related protein Rap-1A
Synonyms:
C21KG | G-22K | GTP-binding protein smg p21A | KREV1 | RAP1A | RAP1A_HUMAN | Ras-related protein Krev-1
Type:
PROTEIN
Mol. Mass.:
20986.96
Organism:
Homo sapiens (Human)
Description:
ChEMBL_676192
Residue:
184
Sequence:
MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLEDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKSCLLL
  
Inhibitor
Name:
BDBM50310364
Synonyms:
CHEMBL1077126 | YESSOTOXIN
Type:
Small organic molecule
Emp. Form.:
C55H80O20S2
Mol. Mass.:
1125.343
SMILES:
C[C@H]1CC[C@]2(C)O[C@]3(C)CC[C@@H]4O[C@@H]5C[C@@H]6O[C@@H]7C[C@H](OS([O-])(=O)=O)[C@@](C)(CCOS([O-])(=O)=O)O[C@H]7C[C@H]6O[C@H]5C[C@H]4O[C@H]3C[C@H]2O[C@H]2C[C@H]3O[C@H]4C[C@H]5O[C@@H](C(=C)C[C@@H]5O[C@]4(C)C[C@@H]3O[C@H]12)[C@](C)(O)\C=C\C(=C)CC=C |r|
Structure:
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