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Target
Translocator protein
Ligand
BDBM50350912
Substrate
n/a
Meas. Tech.
ChEMBL_763593 (CHEMBL1820034)
Ki
1.19±n/a nM
Citation
 Damont, A; Boisgard, R; Kuhnast, B; Lemée, F; Raggiri, G; Scarf, AM; Da Pozzo, E; Selleri, S; Martini, C; Tavitian, B; Kassiou, M; Dollé, F Synthesis of 6-[¹8F]fluoro-PBR28, a novel radiotracer for imaging the TSPO 18 kDa with PET. Bioorg Med Chem Lett 21:4819-22 (2011) [PubMed]  Article 
Target
Name:
Translocator protein
Synonyms:
BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN
Type:
Enzyme
Mol. Mass.:
18834.74
Organism:
Homo sapiens (Human)
Description:
P30536
Residue:
169
Sequence:
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
  
Inhibitor
Name:
BDBM50350912
Synonyms:
CHEMBL1817978
Type:
Small organic molecule
Emp. Form.:
C21H19FN2O3
Mol. Mass.:
366.3856
SMILES:
COc1ccccc1CN(C(C)=O)c1cnc(F)cc1Oc1ccccc1
Structure:
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