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Target
Taste receptor type 2 member 31
Ligand
BDBM50312648
Substrate
n/a
Meas. Tech.
ChEMBL_821056 (CHEMBL2039382)
IC50
3600±n/a nM
Citation
 Kinghorn, AD; Pan, L; Fletcher, JN; Chai, H The relevance of higher plants in lead compound discovery programs. J Nat Prod 74:1539-55 (2011) [PubMed]  Article 
Target
Name:
Taste receptor type 2 member 31
Synonyms:
T2R31 | T2R31_HUMAN | T2R44 | T2R53 | TAS2R31 | TAS2R44 | Taste receptor type 2 member 44 | Taste receptor type 2 member 53
Type:
PROTEIN
Mol. Mass.:
35304.19
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1454723
Residue:
309
Sequence:
MTTFIPIIFSSVVVVLFVIGNFANGFIALVNSIERVKRQKISFADQILTALAVSRVGLLWVLLLNWYSTVFNPAFYSVEVRTTAYNVWAVTGHFSNWLATSLSIFYLLKIANFSNLIFLHLKRRVKSVILVMLLGPLLFLACQLFVINMKEIVRTKEYEGNLTWKIKLRSAVYLSDATVTTLGNLVPFTLTLLCFLLLICSLCKHLKKMQLHGKGSQDPSTKVHIKALQTVIFFLLLCAVYFLSIMISVWSFGSLENKPVFMFCKAIRFSYPSIHPFILIWGNKKLKQTFLSVLRQVRYWVKGEKPSSP
  
Inhibitor
Name:
BDBM50312648
Synonyms:
(2S)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-2,3-dihydro-4H-chromen-4-one | (S)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxychroman-4-one | 5,4'-dihydroxy-7-methoxyflavanone | 7-O-methylnaringenin | CHEMBL448297 | Sakuranetin
Type:
Small organic molecule
Emp. Form.:
C16H14O5
Mol. Mass.:
286.2794
SMILES:
COc1cc(O)c2C(=O)C[C@H](Oc2c1)c1ccc(O)cc1 |r|
Structure:
Search PDB for entries with ligand similarity: