Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM50020222
Substrate
n/a
Meas. Tech.
ChEMBL_856121 (CHEMBL2162509)
Ki
1430±n/a nM
Citation
 Clark, AH; McCorvy, JD; Conley, JM; Williams, WK; Bekkam, M; Watts, VJ; Nichols, DE Identification of a 2-phenyl-substituted octahydrobenzo[f]quinoline as a dopamine D3 receptor-selective full agonist ligand. Bioorg Med Chem 20:6366-74 (2012) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50020222
Synonyms:
(+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol | (+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin | (R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol | 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol | 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol | 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN) | 7-OH-DPAT | 7-OH-DPAT,(+) | 7-OH-DPAT,(-) | 7-hydroxy-2-(dipropylamino)tetralin | CHEMBL1255966 | CHEMBL285755
Type:
Small organic molecule
Emp. Form.:
C16H25NO
Mol. Mass.:
247.3758
SMILES:
CCCN(CCC)C1CCc2ccc(O)cc2C1
Structure:
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