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Target
Somatostatin receptor type 1
Ligand
BDBM50423311
Substrate
n/a
Meas. Tech.
ChEMBL_456079 (CHEMBL888088)
Kd
3.6±n/a nM
Citation
 Troxler, T; Hoyer, D; Langenegger, D; Neumann, P; Pfäffli, P; Schoeffter, P; Sorg, D; Swoboda, R; Hurth, K Identification and SAR of potent and selective non-peptide obeline somatostatin sst1 receptor antagonists. Bioorg Med Chem Lett 17:3983-7 (2007) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 1
Synonyms:
SOMATOSTATIN SST1 | SRIF-2 | SS1R | SSR1_RAT | Somatostatin receptor | Somatostatin receptor type 1 | Sstr1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42752.93
Organism:
RAT
Description:
SOMATOSTATIN SST1 SSTR1 RAT::P28646
Residue:
391
Sequence:
MFPNGTAPSPTSSPSSSPGGCGEGVCSRGPGSGAADGMEEPGRNSSQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQDDATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKSRAYSVEDFQPENLESGGVFRNGTCASRISTL
  
Inhibitor
Name:
BDBM50423311
Synonyms:
CHEMBL399267
Type:
Small organic molecule
Emp. Form.:
C26H31ClN4O4
Mol. Mass.:
499.002
SMILES:
COc1ccc(Cl)c2C[C@@H]3[C@H](C[C@H](CN3C)C(=O)N3CCN(CC3)c3ccc(cc3)[N+]([O-])=O)Cc12
Structure:
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