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Target
GTP-binding protein Rheb
Ligand
BDBM29608
Substrate
n/a
Meas. Tech.
ChEMBL_1287899 (CHEMBL3112318)
Kd
1800000±n/a nM
Citation
 Schöpel, M; Jockers, KF; Düppe, PM; Autzen, J; Potheraveedu, VN; Ince, S; Yip, KT; Heumann, R; Herrmann, C; Scherkenbeck, J; Stoll, R Bisphenol A binds to Ras proteins and competes with guanine nucleotide exchange: implications for GTPase-selective antagonists. J Med Chem 56:9664-72 (2014) [PubMed]  Article 
Target
Name:
GTP-binding protein Rheb
Synonyms:
RHEB | RHEB2 | RHEB_HUMAN | Ras homolog enriched in brain
Type:
PROTEIN
Mol. Mass.:
20495.73
Organism:
Homo sapiens (Human)
Description:
ChEMBL_108016
Residue:
184
Sequence:
MPQSKSRKIAILGYRSVGKSSLTIQFVEGQFVDSYDPTIENTFTKLITVNGQEYHLQLVDTAGQDEYSIFPQTYSIDINGYILVYSVTSIKSFEVIKVIHGKLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFRRIILEAEKMDGAASQGKSSCSVM
  
Inhibitor
Name:
BDBM29608
Synonyms:
Bisphenol A (BPA) | Diphenylolpropane | US9688816, L
Type:
Small organic molecule
Emp. Form.:
C15H16O2
Mol. Mass.:
228.2863
SMILES:
CC(C)(c1ccc(O)cc1)c1ccc(O)cc1
Structure:
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