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Target
G-protein coupled receptor 183
Ligand
BDBM50011716
Substrate
n/a
Meas. Tech.
ChEMBL_1352282 (CHEMBL3269346)
IC50
0.300000±n/a nM
Citation
 Gessier, F; Preuss, I; Yin, H; Rosenkilde, MM; Laurent, S; Endres, R; Chen, YA; Marsilje, TH; Seuwen, K; Nguyen, DG; Sailer, AW Identification and characterization of small molecule modulators of the Epstein-Barr virus-induced gene 2 (EBI2) receptor. J Med Chem 57:3358-68 (2014) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 183
Synonyms:
EBI2 | GP183_HUMAN | GPR183
Type:
PROTEIN
Mol. Mass.:
41245.79
Organism:
Homo sapiens (Human)
Description:
ChEMBL_108311
Residue:
361
Sequence:
MDIQMANNFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVNFMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERITCMEYPNFEETKSLPWILLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNKKALNTIILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKVMRMLKRQVSVSISSAVKSAPEENSREMTETQMMIHSKSSNGK
  
Inhibitor
Name:
BDBM50011716
Synonyms:
CHEMBL3262896
Type:
Small organic molecule
Emp. Form.:
C21H21BrN2O3
Mol. Mass.:
429.307
SMILES:
COc1ccc(cc1)C(=O)N1CCN(CC1)C(=O)\C=C\c1ccc(Br)cc1
Structure:
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