Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50187591
Substrate
n/a
Meas. Tech.
ChEMBL_1590515 (CHEMBL3831097)
Ki
310±n/a nM
Citation
 Szymanska, E; Drabczynska, A; Karcz, T; Müller, CE; Köse, M; Karolak-Wojciechowska, J; Fruzinski, A; Schabikowski, J; Doroz-Plonka, A; Handzlik, J; Kiec-Kononowicz, K Similarities and differences in affinity and binding modes of tricyclic pyrimido- and pyrazinoxanthines at human and rat adenosine receptors. Bioorg Med Chem 24:4347-4362 (2016) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50187591
Synonyms:
CHEMBL3827331
Type:
Small organic molecule
Emp. Form.:
C30H46N6O3
Mol. Mass.:
538.7246
SMILES:
CCCCn1c2nc3N(CCc4ccc(OCCN(CC)CC)cc4)CCCn3c2c(=O)n(CCCC)c1=O
Structure:
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