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Target
D(2) dopamine receptor
Ligand
BDBM50207047
Substrate
n/a
Meas. Tech.
ChEMBL_1629510 (CHEMBL3872136)
Ki
251±n/a nM
Citation
 Saavedra, OM; Karila, D; Brossard, D; Rojas, A; Dupuis, D; Gohier, A; Mannoury la Cour, C; Millan, MJ; Ortuno, JC; Hanessian, S Design and synthesis of novel N-sulfonyl-2-indoles that behave as 5-HT Bioorg Med Chem 25:38-52 (2017) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50207047
Synonyms:
CHEMBL3910287
Type:
Small organic molecule
Emp. Form.:
C28H29N3O3S
Mol. Mass.:
487.613
SMILES:
CN(CCc1ccc(NC(C)=O)cc1)CC1Cc2ccc3n(ccc3c12)S(=O)(=O)c1ccccc1
Structure:
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