Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM85391
Substrate
n/a
Ki
42±n/a nM
Comments
PDSP_1520
Citation
 Ganapathy, ME; Prasad, PD; Huang, W; Seth, P; Leibach, FH; Ganapathy, V Molecular and ligand-binding characterization of the sigma-receptor in the Jurkat human T lymphocyte cell line. J Pharmacol Exp Ther 289:251-60 (1999) [PubMed] 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25124.85
Organism:
Homo sapiens (Human)
Description:
Q99720
Residue:
223
Sequence:
MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM85391
Synonyms:
CAS_85976-54-1 | NSC_149136 | PPP, (+)
Type:
Small organic molecule
Emp. Form.:
C12H16N5O13P3
Mol. Mass.:
531.2024
SMILES:
OC1CC(OC1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1cnc2c1n1ccnc1[nH]c2=O
Structure:
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