Reaction Details Report a problem with these data
Target
Gamma-aminobutyric acid receptor subunit rho-3
Ligand
BDBM23183
Substrate
n/a
Ki
460±n/a nM
Comments
PDSP_1260
Citation
 Chang, Y; Covey, DF; Weiss, DS Correlation of the apparent affinities and efficacies of gamma-aminobutyric acid(C) receptor agonists. Mol Pharmacol 58:1375-80 (2000) [PubMed]  Article 
Target
Name:
Gamma-aminobutyric acid receptor subunit rho-3
Synonyms:
GABA B rho 1 | GABRR3 | GBRR3_HUMAN | Gamma-aminobutyric acid receptor subunit rho-3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
54281.08
Organism:
Homo sapiens (Human)
Description:
GABA B rho 1 0 HUMAN::A8MPY1
Residue:
467
Sequence:
MVLAFQLVSFTYIWIILKPNVCAASNIKMTHQRCSSSMKQTCKQETRMKKDDSTKARPQKYEQLLHIEDNDFAMRPGFGGSPVPVGIDVHVESIDSISETNMDFTMTFYLRHYWKDERLSFPSTANKSMTFDHRLTRKIWVPDIFFVHSKRSFIHDTTMENIMLRVHPDGNVLLSLRITVSAMCFMDFSRFPLDTQNCSLELESYAYNEDDLMLYWKHGNKSLNTEEHMSLSQFFIEDFSASSGLAFYSSTGWYNRLFINFVLRRHVFFFVLQTYFPAILMVMLSWVSFWIDRRAVPARVSLGITTVLTMSTIITAVSASMPQVSYLKAVDVYLWVSSLFVFLSVIEYAAVNYLTTVEERKQFKKTGKISRMYNIDAVQAMAFDGCYHDSEIDMDQTSLSLNSEDFMRRKSICSPSTDSSRIKRRKSLGGHVGRIILENNHVIDTYSRILFPIVYILFNLFYWGVYV
  
Inhibitor
Name:
BDBM23183
Synonyms:
5-(aminomethyl)-1,2-oxazol-3-ol | Agarin | CHEMBL273481 | Muscimol | Pantherine
Type:
GABA Agonist
Emp. Form.:
C4H6N2O2
Mol. Mass.:
114.1026
SMILES:
NCc1cc(=O)[nH]o1
Structure:
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