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Target
Delta-type opioid receptor
Ligand
BDBM88444
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>92496±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM88444
Synonyms:
2-(phenylthio)-N-[5-(2-phenylvinyl)-1,3,4-thiadiazol-2-yl]acetamide | 2-(phenylthio)-N-[5-[(E)-styryl]-1,3,4-thiadiazol-2-yl]acetamide | MLS000580100 | N-[5-[(E)-2-phenylethenyl]-1,3,4-thiadiazol-2-yl]-2-(phenylthio)acetamide | N-[5-[(E)-2-phenylethenyl]-1,3,4-thiadiazol-2-yl]-2-phenylsulfanyl-ethanamide | N-[5-[(E)-2-phenylethenyl]-1,3,4-thiadiazol-2-yl]-2-phenylsulfanylacetamide | SMR000199630 | cid_5739567
Type:
Small organic molecule
Emp. Form.:
C18H15N3OS2
Mol. Mass.:
353.461
SMILES:
O=C(CSc1ccccc1)Nc1nnc(\C=C\c2ccccc2)s1
Structure:
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