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Target
Delta-type opioid receptor
Ligand
BDBM88446
Substrate
n/a
Meas. Tech.
Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>92469±n/a nM
Citation
 PubChem, PC Counterscreen for biased ligands (agonists) of the melanocortin 4 receptor (MC4R): Luminescence-based cell-based high throughput dose response assay to identify agonists of heterodimerization of the mu 1 (OPRM1) and delta 1 (OPRD1) opioid receptors PubChem Bioassay (2012)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM88446
Synonyms:
1,3-benzothiazol-2-yl-[(E)-[1-[2-(3-methylphenoxy)ethyl]pyrrol-2-yl]methyleneamino]amine | MLS000589686 | N-Benzothiazol-2-yl-N'-[1-[1-(2-m-tolyloxy-ethyl)-1H-pyrrol-2-yl]-meth-(E)-ylidene]-hydrazine | N-[(E)-[1-[2-(3-methylphenoxy)ethyl]-2-pyrrolyl]methylideneamino]-1,3-benzothiazol-2-amine | N-[(E)-[1-[2-(3-methylphenoxy)ethyl]pyrrol-2-yl]methylideneamino]-1,3-benzothiazol-2-amine | SMR000219486 | cid_6891712
Type:
Small organic molecule
Emp. Form.:
C21H20N4OS
Mol. Mass.:
376.475
SMILES:
Cc1cccc(OCCn2cccc2CN=Nc2nc3ccccc3s2)c1 |w:15.15|
Structure:
Search PDB for entries with ligand similarity: