Reaction Details Report a problem with these data
Target
Alpha-(1,3)-fucosyltransferase 7
Ligand
BDBM50335808
Substrate
n/a
Meas. Tech.
SPA Assay
pH
7.3000±0.0000
Temperature
295.1500±0.0000 K
IC50
115000±18000 nM
Citation
 Niu, X; Fan, X; Sun, J; Ting, P; Narula, S; Lundell, D Inhibition of fucosyltransferase VII by gallic acid and its derivatives. Arch Biochem Biophys 425:51-7 (2004) [PubMed]  Article 
Target
Name:
Alpha-(1,3)-fucosyltransferase 7
Synonyms:
Fucosyltransferase VII | Fuct VII | Alpha-(1,3)-fucosyltransferase VII | FUT7_HUMAN | FUT7
Type:
n/a
Mol. Mass.:
39259.56
Organism:
Human
Description:
Q11130
Residue:
342
Sequence:
MNNAGHGPTRRLRGLGVLAGVALLAALWLLWLLGSAPRGTPAPQPTITILVWHWPFTDQPPELPSDTCTRYGIARCHLSANRSLLASADAVVFHHRELQTRRSHLPLAQRPRGQPWVWASMESPSHTHGLSHLRGIFNWVLSYRRDSDIFVPYGRLEPHWGPSPPLPAKSRVAAWVVSNFQERQLRARLYRQLAPHLRVDVFGRANGRPLCASCLVPTVAQYRFYLSFENSQHRDYITEKFWRNALVAGTVPVVLGPPRATYEAFVPADAFVHVDDFGSARELAAFLTGMNESRYQRFFAWRDRLRVRLFTDWRERFCAICDRYPHLPRSQVYEDLEGWFQA
  
Inhibitor
Name:
BDBM50335808
Synonyms:
2,5-Dihydroxybenzoate, VI | gentisic acid | CHEMBL1461 | 2,5-dihydroxybenzoic acid
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: