Reaction Details Report a problem with these data
Target
Histone H1.0
Ligand
BDBM50130293
Substrate
n/a
Meas. Tech.
Binding Assay
Ki
28±0.0 nM
Citation
 Mates, S; Fienberg, A; Wennogle, L Methods and compositions for sleep disorders and other disorders US Patent  US8598119 Publication Date 12/3/2013 
Target
Name:
Histone H1.0
Synonyms:
H1-0 | H10_HUMAN | H1F0 | H1FV | Histone H1
Type:
Cell-surface receptors
Mol. Mass.:
20917.09
Organism:
Homo sapiens (Human)
Description:
P07305
Residue:
194
Sequence:
MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVKPKAKSSAKRAGKKK
  
Inhibitor
Name:
BDBM50130293
Synonyms:
7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one | ARIPIPRAZOLE | CHEMBL1112 | US10174011, aripiprazole | US10752588, Compound Aripiprazole | US11498896, Compound Aripiprazole | US9018213, aripprazole | US9156822, Aripiprazole
Type:
Small organic molecule
Emp. Form.:
C23H27Cl2N3O2
Mol. Mass.:
448.385
SMILES:
Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl
Structure:
Search PDB for entries with ligand similarity: