Found 340 with Last Name = 'wennogle' and Initial = 'l' TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
Intra-Cellular Therapies
US Patent
Intra-Cellular Therapies
US Patent
Affinity DataKi: 0.100nMAssay Description:Assay: The following phosphodiesterase enzymes may be used: 3′,5′-cyclic-nucleotide-specific bovine brain phosphodiesterase (Sigma, St. L...More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
Intra-Cellular Therapies
US Patent
Intra-Cellular Therapies
US Patent
Affinity DataKi: 0.100nM ΔG°: -58.0kJ/molepH: 7.5 T: 2°CAssay Description:Materials: All chemicals are available from Sigma-Aldrich (St. Louis, Mo.) except for IMAP reagents (reaction buffer, binding buffer, FL-GMP and IMAP...More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
Intra-Cellular Therapies
US Patent
Intra-Cellular Therapies
US Patent
Affinity DataKi: 0.200nMAssay Description:Assay: The following phosphodiesterase enzymes may be used: 3′,5′-cyclic-nucleotide-specific bovine brain phosphodiesterase (Sigma, St. L...More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
Intra-Cellular Therapies
US Patent
Intra-Cellular Therapies
US Patent
Affinity DataKi: 0.200nM ΔG°: -56.3kJ/molepH: 7.5 T: 2°CAssay Description:Materials: All chemicals are available from Sigma-Aldrich (St. Louis, Mo.) except for IMAP reagents (reaction buffer, binding buffer, FL-GMP and IMAP...More data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Binding assay using 5-HT2A, Dopamine D2, SERT, αA1, 5-HT2C and H1 Receptors.More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
Intra-Cellular Therapies
US Patent
Intra-Cellular Therapies
US Patent
Affinity DataKi: 0.300nM ΔG°: -55.3kJ/molepH: 7.5 T: 2°CAssay Description:Materials: All chemicals are available from Sigma-Aldrich (St. Louis, Mo.) except for IMAP reagents (reaction buffer, binding buffer, FL-GMP and IMAP...More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
Intra-Cellular Therapies
US Patent
Intra-Cellular Therapies
US Patent
Affinity DataKi: 0.300nMAssay Description:Assay: The following phosphodiesterase enzymes may be used: 3′,5′-cyclic-nucleotide-specific bovine brain phosphodiesterase (Sigma, St. L...More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Homo sapiens (Human))
Intra-Cellular Therapies
US Patent
Intra-Cellular Therapies
US Patent
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
Intra-Cellular Therapies
US Patent
Intra-Cellular Therapies
US Patent
Affinity DataKi: 0.400nM ΔG°: -54.5kJ/molepH: 7.5 T: 2°CAssay Description:Materials: All chemicals are available from Sigma-Aldrich (St. Louis, Mo.) except for IMAP reagents (reaction buffer, binding buffer, FL-GMP and IMAP...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding assay using 5-HT2A, Dopamine D2, SERT, αA1, 5-HT2C and H1 Receptors.More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
Intra-Cellular Therapies
US Patent
Intra-Cellular Therapies
US Patent
Affinity DataKi: 0.5nMAssay Description:Assay: The following phosphodiesterase enzymes may be used: 3′,5′-cyclic-nucleotide-specific bovine brain phosphodiesterase (Sigma, St. L...More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
Intra-Cellular Therapies
US Patent
Intra-Cellular Therapies
US Patent
Affinity DataKi: 0.5nM ΔG°: -54.0kJ/molepH: 7.5 T: 2°CAssay Description:Materials: All chemicals are available from Sigma-Aldrich (St. Louis, Mo.) except for IMAP reagents (reaction buffer, binding buffer, FL-GMP and IMAP...More data for this Ligand-Target Pair
Affinity DataKi: 0.540nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding assay using 5-HT2A, Dopamine D2, SERT, αA1, 5-HT2C and H1 Receptors.More data for this Ligand-Target Pair
Affinity DataKi: 0.890nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.940nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Homo sapiens (Human))
Intra-Cellular Therapies
US Patent
Intra-Cellular Therapies
US Patent
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
Intra-Cellular Therapies
US Patent
Intra-Cellular Therapies
US Patent
Affinity DataKi: 1nM ΔG°: -52.2kJ/molepH: 7.5 T: 2°CAssay Description:Materials: All chemicals are available from Sigma-Aldrich (St. Louis, Mo.) except for IMAP reagents (reaction buffer, binding buffer, FL-GMP and IMAP...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding assay using 5-HT2A, Dopamine D2, SERT, αA1, 5-HT2C and H1 Receptors.More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of histamine H1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Binding assay using 5-HT2A, Dopamine D2, SERT, αA1, 5-HT2C and H1 Receptors.More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding assay using 5-HT2A, Dopamine D2, SERT, αA1, 5-HT2C and H1 Receptors.More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of histamine H1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Binding assay using 5-HT2A, Dopamine D2, SERT, αA1, 5-HT2C and H1 Receptors.More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Binding assay using 5-HT2A, Dopamine D2, SERT, αA1, 5-HT2C and H1 Receptors.More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Homo sapiens (Human))
Intra-Cellular Therapies
US Patent
Intra-Cellular Therapies
US Patent
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
Intra-Cellular Therapies
US Patent
Intra-Cellular Therapies
US Patent
Affinity DataKi: 4nM ΔG°: -48.7kJ/molepH: 7.5 T: 2°CAssay Description:Materials: All chemicals are available from Sigma-Aldrich (St. Louis, Mo.) except for IMAP reagents (reaction buffer, binding buffer, FL-GMP and IMAP...More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Homo sapiens (Human))
Intra-Cellular Therapies
US Patent
Intra-Cellular Therapies
US Patent
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
Intra-Cellular Therapies
US Patent
Intra-Cellular Therapies
US Patent
Affinity DataKi: 4nM ΔG°: -48.7kJ/molepH: 7.5 T: 2°CAssay Description:Materials: All chemicals are available from Sigma-Aldrich (St. Louis, Mo.) except for IMAP reagents (reaction buffer, binding buffer, FL-GMP and IMAP...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Intra-Cellular Therapies
US Patent
Intra-Cellular Therapies
US Patent
Affinity DataKi: 4.20nMAssay Description:Assay Type: BindingSpecies: HumanOrigin: Recombinant/CHO cellsLigand: [3H]-NisoxetineLigand [M]: 1.00E-09Kd (Binding Affinity): 3.00E-09Bmax: 10 pmol...More data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Binding assay using 5-HT2A, Dopamine D2, SERT, αA1, 5-HT2C and H1 Receptors.More data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Displacement of [125]DOI from human recombinant full length 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
