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Target
Kappa-type opioid receptor
Ligand
BDBM155858
Substrate
n/a
Meas. Tech.
enzyme assay
IC50
1.40±n/a nM
Citation
 Roberts, E; Guerrero, MA; Urbano, M; Rosen, H Kappa opioid ligands US Patent  US10118915 Publication Date 11/6/2018 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM155858
Synonyms:
US10118915, Compound 95 | US9682966, 95
Type:
Small organic molecule
Emp. Form.:
C22H34N4O3
Mol. Mass.:
402.5304
SMILES:
CCCC(=O)Nc1cnc(N2CCC(CC2)NC2CCCCC2)c(c1)C(=O)OC
Structure:
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