Target
Resistance to inhibitors of cholinesterase protein 3
Ligand
BDBM444829
Substrate
n/a
Meas. Tech.
functional assay
EC50
320±30 nM
Citation
 Martin, RJRobertson, APVanVeller, BDu, XZheng, F (S)-5-ethynyl-anabasine, derivatives thereof, and related compositions and methods of making and using US Patent  US10667515 Publication Date 6/2/2020 
Target
Name:
Resistance to inhibitors of cholinesterase protein 3
Synonyms:
F1L1D9_ASCSU
Type:
Protein
Mol. Mass.:
39160.01
Organism:
Pig roundworm
Description:
F1L1D9
Residue:
346
Sequence:
MPNSETATRSRRRRRRSSDDDDGPVSGWKMGLVVGVVVLCFGMLYPSLFHPMISSFFSKPPPPQQTIPNRPPIHPSMSSPRARPDIHPGMRMAAAQAEATATSSSKGMFAWMLPLYTVGVVVFLIYTLVKSKRKKQRRRHAYSSDESESYGEDDEYEQRGPGVHNLGRRKLRSLQERLKQTELAMSKILEQLGTISVDPTQGTVPQNLENTVDQKSKTNGESKKADVDKEHYLRDLEKALREFKHLSNSYNKEERKRRGESLSEEEEMNEDEFEEEMDEDEGTEEKSHGGGGSAGSAAEDEAENCSEDEREEKQEDDGKKGEDEVLVPAVEQHVQQTKPHKRSKRT
  
Inhibitor
Name:
BDBM444829
Synonyms:
US10667515, Compound (S)-5-bromo-anabasine
Type:
Small organic molecule
Emp. Form.:
C10H13BrN2
Mol. Mass.:
241.128
SMILES:
Brc1cncc(c1)[C@@H]1CCCCN1 |r|
Structure:
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