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Target
Resistance to inhibitors of cholinesterase protein 3
Ligand
BDBM50100716
Substrate
n/a
Meas. Tech.
functional assay
EC50
12180±290 nM
Citation
 Martin, RJ; Robertson, AP; VanVeller, B; Du, X; Zheng, F (S)-5-ethynyl-anabasine, derivatives thereof, and related compositions and methods of making and using US Patent  US10667515 Publication Date 6/2/2020 
Target
Name:
Resistance to inhibitors of cholinesterase protein 3
Synonyms:
F1L1D9_ASCSU
Type:
Protein
Mol. Mass.:
39160.01
Organism:
Pig roundworm
Description:
F1L1D9
Residue:
346
Sequence:
MPNSETATRSRRRRRRSSDDDDGPVSGWKMGLVVGVVVLCFGMLYPSLFHPMISSFFSKPPPPQQTIPNRPPIHPSMSSPRARPDIHPGMRMAAAQAEATATSSSKGMFAWMLPLYTVGVVVFLIYTLVKSKRKKQRRRHAYSSDESESYGEDDEYEQRGPGVHNLGRRKLRSLQERLKQTELAMSKILEQLGTISVDPTQGTVPQNLENTVDQKSKTNGESKKADVDKEHYLRDLEKALREFKHLSNSYNKEERKRRGESLSEEEEMNEDEFEEEMDEDEGTEEKSHGGGGSAGSAAEDEAENCSEDEREEKQEDDGKKGEDEVLVPAVEQHVQQTKPHKRSKRT
  
Inhibitor
Name:
BDBM50100716
Synonyms:
5-(1-Methyl-pyrrolidin-2-yl)-pyridin-2-ylamine | CHEMBL70774 | US10667515, Compound 6-AN
Type:
Small organic molecule
Emp. Form.:
C10H15N3
Mol. Mass.:
177.2462
SMILES:
CN1CCCC1c1ccc(N)nc1
Structure:
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