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Target
N-formyl peptide receptor 2
Ligand
BDBM466546
Substrate
n/a
Meas. Tech.
FLIPR
EC50
4.00±n/a nM
Citation
 Viswanath, V; Beard, RL; Donello, JE; Hsia, E Use of agonists of formyl peptide receptor 2 for treating dermatological diseases US Patent  US10799518 Publication Date 10/13/2020 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM466546
Synonyms:
US10799518, Compound 14 | rel-(2R,3 S)-3-[(4- brornophenyl)carbarnoyl]spiro [bicyclo[2.2.1]heptane-7,1'- cyclopropane]-2-carboxylic acid
Type:
Small organic molecule
Emp. Form.:
C17H18BrNO3
Mol. Mass.:
364.234
SMILES:
OC(=O)C1C2CCC(C1C(=O)Nc1ccc(Br)cc1)C21CC1 |TLB:9:8:6.5:19,THB:1:3:6.5:19|
Structure:
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