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Target
Alpha-synuclein
Ligand
BDBM481155
Substrate
n/a
Meas. Tech.
In Vitro Inhibition Assay
Ki
20.7±9 nM
Citation
 Routier, S; Suzenet, F; Chalon, S; Buron, F; Vercouillie, J; Melki, R; Boiaryna, L; Guilloteau, D; Pieri, L Compounds for using in imaging and particularly for the diagnosis of neurodegenerative diseases US Patent  US10906900 Publication Date 2/2/2021 
Target
Name:
Alpha-synuclein
Synonyms:
NACP | PARK1 | SNCA | SYUA_HUMAN
Type:
Protein
Mol. Mass.:
14451.42
Organism:
Homo sapiens (Human)
Description:
P37840
Residue:
140
Sequence:
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
  
Inhibitor
Name:
BDBM481155
Synonyms:
US10906900, Reference 22h
Type:
Small organic molecule
Emp. Form.:
C17H14FN3
Mol. Mass.:
279.3116
SMILES:
CN(C)c1ccc(cc1)C#Cc1cc2c(F)ccnc2[nH]1
Structure:
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