Target

Ligand

Substrate

Meas. Tech.

Kinase Inhibition Assay

Temperature

310.15±n/a K

Citation

 Conde, S; Perez, DI; Martinez, A; Perez, C; Moreno, FJ Thienyl and phenyl alpha-halomethyl ketones: new inhibitors of glycogen synthase kinase (GSK-3 beta) from a library of compound searching. J Med Chem 46:4631-3 (2003) [PubMed]  Article Copy BDB DOI

More Info.:

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Name:

Glycogen synthase kinase-3 beta [7-25]

Synonyms:

G1T8E2_RABIT | GSK-3, beta | GSK3B | Glycogen Synthase Kinase-3, beta

Type:

Enzyme fragment

Mol. Mass.:

1972.14

Organism:

Oryctolagus cuniculus (rabbit)

Description:

Glycogen Synthase Kinase-3 is the beta isoform of the rabbit enzyme produced in E.coli.. Only partial sequence is available.

Residue:

19

Sequence:

TTSFAESCKPVQQPSAFGS

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Blast E-value cutoff:

Name:

BDBM7868

Synonyms:

2-chloro-1-(3,4-dibromothiophen-2-yl)ethan-1-one | Chloromethyl Thienyl Ketone deriv. 16

Type:

Small organic molecule

Emp. Form.:

C6H3Br2ClOS

Mol. Mass.:

318.413

SMILES:

ClCC(=O)c1scc(Br)c1Br

Structure:

Search PDB for entries with ligand similarity:

Similarity to this molecule at least:

Name:

GSK-3 Peptide Substrate

Synonyms:

GS-1 Peptide | Phospho-GS2 Substrate Peptide

Type:

Peptide

Mol. Mass.:

3045.17

Organism:

n/a

Description:

n/a

Residue:

27

Sequence:

YRRAAVPPSPSLSRHSSPHQSPEDEEE