Compile Data Set for Download or QSAR
Report error Found 1711 of affinity data for UniProtKB/TrEMBL: O15552
TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271169BDBM271169(7-(2-fluorobenzenesulfonyl)-2-methyl-4-[(2R)-2-(tr...)
Affinity DataEC50:  1nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271163BDBM271163(7-(4-chloro-2-fluorobenzenesulfonyl)-2-methyl-4-[(...)
Affinity DataEC50:  1nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271179BDBM271179(7-(2-fluorobenzenesulfonyl)-N2-methyl-4-(2-methylm...)
Affinity DataEC50:  1nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271162BDBM271162(7-(2-fluoro-4-methoxybenzenesulfonyl)-2-methyl-4-[...)
Affinity DataEC50:  1nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271161BDBM271161(7-(2,3-difluorobenzenesulfonyl)-4-(2,2-dimethylmor...)
Affinity DataEC50:  1nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271111BDBM271111(7-(2-fluorobenzenesulfonyl)-2-methyl-4-[2-(trifluo...)
Affinity DataEC50:  2nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271173BDBM271173(7-(2,5-difluorobenzenesulfonyl)-2-methyl-4-[(2S)-2...)
Affinity DataEC50:  2nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271170BDBM271170(7-(2-fluorobenzenesulfonyl)-2-methyl-4-[(2R)-2-(tr...)
Affinity DataEC50:  2nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271121BDBM271121(7-(benzenesulfonyl)-2-methyl-4-(propan-2-yloxy)-5H...)
Affinity DataEC50:  2nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271119BDBM271119(7-(benzenesulfonyl)-4-(2-methylmorpholin-4-yl)-2-(...)
Affinity DataEC50:  2nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271182BDBM271182(7-(2-fluorobenzenesulfonyl)-2-(methylsulfanyl)-4-[...)
Affinity DataEC50:  2nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271165BDBM271165(7-(2,3-difluorobenzenesulfonyl)-2-methyl-4-[(2S)-2...)
Affinity DataEC50:  2nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271164BDBM271164(7-(2,4-difluorobenzenesulfonyl)-2-methyl-4-[(2S)-2...)
Affinity DataEC50:  2nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271115BDBM271115(4-(2-methylmorpholin-4-yl)-7-(phenylsulfanyl)-5H-p...)
Affinity DataEC50:  2nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271098BDBM271098(7-(benzenesulfonyl)-4-[(2R,5R)-2,5-dimethylmorphol...)
Affinity DataEC50:  2nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271177BDBM271177(7-(4-chloro-2-fluorobenzenesulfonyl)-2-methyl-4-[(...)
Affinity DataEC50:  2nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271112BDBM271112(7-(2-fluoro-4-methoxybenzenesulfonyl)-2-methyl-4-[...)
Affinity DataEC50:  3nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271160BDBM271160(7-(2-fluorobenzenesulfonyl)-2-methyl-4-[(2S)-2-(tr...)
Affinity DataEC50:  3nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271175BDBM271175(4-[(2,2-dimethyloxan-3-yl)oxy]-7-(2-fluorobenzenes...)
Affinity DataEC50:  3nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271172BDBM271172(7-(2-fluoro-4-methoxybenzenesulfonyl)-2-methyl-4-[...)
Affinity DataEC50:  3nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271171BDBM271171(7-(2-fluorobenzenesulfonyl)-2-methyl-4-[(2R)-2-(tr...)
Affinity DataEC50:  3nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271088BDBM271088(4-cyclopentyl-7-(3-fluorobenzenesulfonyl)-2-methyl...)
Affinity DataEC50:  3nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271183BDBM271183(7-(2-fluorobenzenesulfonyl)-2-methyl-4-[2-methyl-2...)
Affinity DataEC50:  3nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271166BDBM271166(7-(2,6-difluorobenzenesulfonyl)-4-(2,2-dimethylmor...)
Affinity DataEC50:  3nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 270890BDBM270890(7-(benzenesulfonyl)-4-(piperidin-1-yl)-5H-pyrrolo[...)
Affinity DataEC50:  3nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271146BDBM271146(7-(3-fluorobenzenesulfonyl)-4-(2-methylmorpholin-4...)
Affinity DataEC50:  3nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271113BDBM271113(4-[(2R,5R)-2,5-dimethylmorpholin-4-yl]-7-(2-fluoro...)
Affinity DataEC50:  3nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271159BDBM271159(7-(4-chloro-2-fluorobenzenesulfonyl)-4-(2,2-dimeth...)
Affinity DataEC50:  4nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271174BDBM271174(7-(2,6-Difluorobenzenesulfonyl)-2-methyl-4-[(2S)-2...)
Affinity DataEC50:  4nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271077BDBM271077(7-(benzenesulfonyl)-4-(2-ethylthiomorpholin-4-yl)-...)
Affinity DataEC50:  4nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271147BDBM271147(7-(2-fluoro-5-methoxybenzenesulfonyl)-2-methyl-4-(...)
Affinity DataEC50:  4nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271142BDBM271142(7-(2,6-difluorobenzenesulfonyl)-2-methyl-4-(2-meth...)
Affinity DataEC50:  5nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271155BDBM271155(7-(2-fluorobenzenesulfonyl)-2-methyl-4-[(1,1,1-tri...)
Affinity DataEC50:  5nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271067BDBM271067(7-(benzenesulfonyl)-4-N-ethyl-4-N-(oxan-4-ylmethyl...)
Affinity DataEC50:  5nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271178BDBM271178(7-(2-fluorobenzenesulfonyl)-4-[(2R)-2-(fluoromethy...)
Affinity DataEC50:  5nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271143BDBM271143(7-(2,4-difluorobenzenesulfonyl)-2-methyl-4-(2-meth...)
Affinity DataEC50:  6nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271062BDBM271062(4-(4,4-difluoropiperidin-1-yl)-7-(3-fluorobenzenes...)
Affinity DataEC50:  6nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271158BDBM271158(3-(benzenesulfonyl)-7-(2,2-dimethylmorpholin-4-yl)...)
Affinity DataEC50:  6nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271057BDBM271057(7-(2-fluorobenzenesulfonyl)-2-methyl-4-{6-oxa-9-az...)
Affinity DataEC50:  6nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271020BDBM271020(7-(benzenesulfonyl)-4-[(2R,6S)-2,6-dimethylmorphol...)
Affinity DataEC50:  6nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271065BDBM271065(7-(benzenesulfonyl)-4-[2-(propan-2-yl)morpholin-4-...)
Affinity DataEC50:  6nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271097BDBM271097(7-(2-fluorobenzenesulfonyl)-2-methyl-4-[(2S)-2-met...)
Affinity DataEC50:  6nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271109BDBM271109(7-(benzenesulfonyl)-4-(1-cyclopropylethoxy)-2-meth...)
Affinity DataEC50:  7nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271103BDBM271103(7-(2-fluorobenzenesulfonyl)-2-methyl-4-(prop-1-en-...)
Affinity DataEC50:  7nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271085BDBM271085(US10059713, Example 206)
Affinity DataEC50:  7nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271075BDBM271075(7-(benzenesulfonyl)-4-(2-methylthiomorpholin-4-yl)...)
Affinity DataEC50:  8nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271154BDBM271154(4-[(RS,SR)-2,3-dimethylmorpholin-4-yl]-7-(2-fluoro...)
Affinity DataEC50:  8nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271056BDBM271056(US10059713, Example 175)
Affinity DataEC50:  8nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271168BDBM271168(7-(2,5-difluorobenzenesulfonyl)-4-(2,2-dimethylmor...)
Affinity DataEC50:  8nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271151BDBM271151(7-(2-fluorobenzenesulfonyl)-2-methyl-4-(propan-2-y...)
Affinity DataEC50:  8nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

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