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Report error Found 188 for UniProtKB: O88871
LigandPNGBDBM24185(CGP35024 | 3-Apmpa | CHEMBL112710 | (3-aminopropyl...)
Affinity DataIC50: 1nMAssay Description:In vitro displacement of [3H]GABA from Gamma-aminobutyric acid type B receptor sites in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetGamma-aminobutyric acid type B receptor subunit 2(Rat)
Abbvie Deutschland

US Patent
LigandPNGBDBM360710(US9828381, 5-1)
Affinity DataEC50:  3nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent

LigandPNGBDBM24184((3-aminopropyl)phosphinic acid | CHEMBL112203 | CG...)
Affinity DataIC50: 3nMAssay Description:In vitro displacement of [3H]GABA from Gamma-aminobutyric acid type B receptor sites in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetGamma-aminobutyric acid type B receptor subunit 2(Rat)
Abbvie Deutschland

US Patent
LigandPNGBDBM360708(US9828381, 4-1)
Affinity DataEC50:  5nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent

LigandPNGBDBM24184((3-aminopropyl)phosphinic acid | CHEMBL112203 | CG...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of [3H]CGP-27492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 2(Rat)
Abbvie Deutschland

US Patent
LigandPNGBDBM360711(US9828381, 5-2)
Affinity DataEC50:  7nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 2(Rat)
Abbvie Deutschland

US Patent
LigandPNGBDBM360706(US9828381, 3-1)
Affinity DataEC50:  8nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 2(Rat)
Abbvie Deutschland

US Patent
LigandPNGBDBM360709(US9828381, 4-2)
Affinity DataEC50:  9nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 2(Rat)
Abbvie Deutschland

US Patent
LigandPNGBDBM360707(US9828381, 3-2)
Affinity DataEC50:  14nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent

LigandPNGBDBM24185(CGP35024 | 3-Apmpa | CHEMBL112710 | (3-aminopropyl...)
Affinity DataIC50: 16nMAssay Description:Inhibition of [3H]CGP-27492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataIC50: 17nMAssay Description:Inhibition of [3H]CGP-27492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataIC50: 30nMAssay Description:Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataIC50: 30nMpH: 7.4Assay Description:In vitro binding affinity against Gamma-aminobutyric acid type B receptor in rat brain synaptic membranes at pH 7.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | CHEMBL70...)
Affinity DataIC50: 30nMAssay Description:In vitro displacement of [3H]GABA from Gamma-aminobutyric acid type B receptor sites in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50032964(4-Amino-3-(4-chloro-phenyl)-butyric acid | (R)-4-A...)
Affinity DataIC50: 32nMAssay Description:Inhibition of [3H]CGP-27492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50287486(3-Amino-propane-1-sulfonic acid benzyl-hydroxy-ami...)
Affinity DataIC50: 40nMAssay Description:Binding affinity against Gamma-aminobutyric acid type B receptor in rat brain synaptosomes after 30 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataIC50: 40nMAssay Description:Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50287485(3-Amino-propane-1-sulfonic acid hydroxy-methyl-ami...)
Affinity DataIC50: 40nMAssay Description:Binding affinity against Gamma-aminobutyric acid type B receptor in rat brain synaptosomes after 30 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

LigandPNGBDBM24189(CHEMBL113304 | [(2S)-3-amino-2-hydroxypropyl](meth...)
Affinity DataIC50: 45nMAssay Description:Inhibition of [3H]CGP-27492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM24189(CHEMBL113304 | [(2S)-3-amino-2-hydroxypropyl](meth...)
Affinity DataIC50: 45nMAssay Description:Inhibition of [3H]CGP-27492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 2(Rat)
Abbvie Deutschland

US Patent
LigandPNGBDBM360693(US9828381, 2-11)
Affinity DataEC50:  57nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent

LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | CHEMBL70...)
Affinity DataIC50: 60nMAssay Description:Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50087276(3-Amino-propane-1-sulfinic acid (Homohypotaurine) ...)
Affinity DataIC50: 60nMAssay Description:Binding affinity against Gamma-aminobutyric acid type B receptor in rat brain synaptosomes after 30 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | cid_119 | Gamma-A...)
Affinity DataIC50: 60nMAssay Description:In vitro displacement of [3H]GABA from Gamma-aminobutyric acid type B receptor sites in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article
PDB3D3D Structure (crystal)
LigandPNGBDBM50032969([3-Amino-2-(4-chloro-phenyl)-2-hydroxy-propyl]-pho...)
Affinity DataIC50: 65nMAssay Description:Inhibition of [3H]CGP-27492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 2(Rat)
Abbvie Deutschland

US Patent
LigandPNGBDBM360704(US9828381, 2-22)
Affinity DataEC50:  70nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 2(Rat)
Abbvie Deutschland

US Patent
LigandPNGBDBM360690(US9828381, 2-8)
Affinity DataEC50:  71nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent

LigandPNGBDBM50287484([(3-Amino-propane-1-sulfonyl)-hydroxy-amino]-aceti...)
Affinity DataIC50: 80nMAssay Description:Binding affinity against Gamma-aminobutyric acid type B receptor in rat brain synaptosomes after 30 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetGamma-aminobutyric acid type B receptor subunit 2(Rat)
Abbvie Deutschland

US Patent
LigandPNGBDBM360717(US9828381, 8-2)
Affinity DataEC50:  87nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent

LigandPNGBDBM50032968((3-Amino-propyl)-difluoromethyl-phosphinic acid | ...)
Affinity DataIC50: 89nMAssay Description:Inhibition of [3H]CGP-27492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 2(Rat)
Abbvie Deutschland

US Patent
LigandPNGBDBM360702(US9828381, 2-20)
Affinity DataEC50:  93nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent

LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | CHEMBL70...)
Affinity DataIC50: 107nMAssay Description:Inhibition of [3H]CGP-27492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 2(Rat)
Abbvie Deutschland

US Patent
LigandPNGBDBM360683(US9828381, 2-1)
Affinity DataEC50:  118nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 2(Rat)
Abbvie Deutschland

US Patent
LigandPNGBDBM360686(US9828381, 2-4)
Affinity DataEC50:  128nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent

LigandPNGBDBM50032964(4-Amino-3-(4-chloro-phenyl)-butyric acid | (R)-4-A...)
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]GABA from Gamma-aminobutyric acid type B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50077628((S)-5-Amino-3-(4-chloro-phenyl)-pentanoic acid | C...)
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]GABA from Gamma-aminobutyric acid type B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50032971(CGP-35582 | (3-Amino-1-methyl-propyl)-methyl-phosp...)
Affinity DataIC50: 140nMAssay Description:Inhibition of [3H]CGP-27492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50077629(5-Amino-4-(4-chloro-phenyl)-pentanoic acid | CHEMB...)
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]GABA from Gamma-aminobutyric acid type B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50032963((S)-4-Amino-3-(4-chloro-phenyl)-butyric acid | CHE...)
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]GABA from Gamma-aminobutyric acid type B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 2(Rat)
Abbvie Deutschland

US Patent
LigandPNGBDBM360687(US9828381, 2-5)
Affinity DataEC50:  146nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 2(Rat)
Abbvie Deutschland

US Patent
LigandPNGBDBM360692(US9828381, 2-10)
Affinity DataEC50:  152nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent

LigandPNGBDBM24189(CHEMBL113304 | [(2S)-3-amino-2-hydroxypropyl](meth...)
Affinity DataIC50: 152nMAssay Description:Inhibition of [3H]CGP-27492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 2(Rat)
Abbvie Deutschland

US Patent
LigandPNGBDBM360696(US9828381, 2-14)
Affinity DataEC50:  165nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 2(Rat)
Abbvie Deutschland

US Patent
LigandPNGBDBM360689(US9828381, 2-7)
Affinity DataEC50:  185nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent

LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | CHEMBL70...)
Affinity DataIC50: 200nMAssay Description:Binding affinity against Gamma-aminobutyric acid type B receptor in rat brain synaptosomes after 30 minutesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | CHEMBL70...)
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]baclofen from Gamma-aminobutyric acid type B receptor of rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50032961((3-Amino-2-hydroxy-propyl)-difluoromethyl-phosphin...)
Affinity DataIC50: 213nMAssay Description:Inhibition of [3H]CGP-27492 binding to Gamma-aminobutyric acid type B receptor of rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid type B receptor subunit 2(Rat)
Abbvie Deutschland

US Patent
LigandPNGBDBM360688(US9828381, 2-6)
Affinity DataEC50:  242nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent

TargetGamma-aminobutyric acid type B receptor subunit 2(Rat)
Abbvie Deutschland

US Patent
LigandPNGBDBM360734(US9828381, 8-19)
Affinity DataEC50:  274nMAssay Description:The composition of the assay mixtures [in a final volume of 200 μL in 96-well U-bottom plates (Greiner) was as follows: 50 mM Tris-HCl buffer, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent

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