Compile Data Set for Download or QSAR
Report error Found 418 of affinity data for UniProtKB/TrEMBL: P11150
TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151423BDBM151423(US8987314, B234)
Affinity DataIC50: 0.5nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151465BDBM151465(US8987314, B276)
Affinity DataIC50: 0.800nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151397BDBM151397(US8987314, B208)
Affinity DataIC50: 0.800nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 50525871BDBM50525871(CHEMBL4460999)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of hepatic lipase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151421BDBM151421(US8987314, B232)
Affinity DataIC50: 0.800nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151494BDBM151494(US8987314, B305)
Affinity DataIC50: 1nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151266BDBM151266(US8987314, B62)
Affinity DataIC50: 1nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151441BDBM151441(US8987314, B252)
Affinity DataIC50: 1.40nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151496BDBM151496(US8987314, B307)
Affinity DataIC50: 1.5nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151399BDBM151399(US8987314, B210)
Affinity DataIC50: 1.90nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151268BDBM151268(US8987314, B64)
Affinity DataIC50: 1.90nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 50506499BDBM50506499(CHEMBL4463265)
Affinity DataIC50: 2nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151554BDBM151554(US8987314, B365)
Affinity DataIC50: 2.10nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151292BDBM151292(US8987314, B88)
Affinity DataIC50: 2.20nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151432BDBM151432(US8987314, B243)
Affinity DataIC50: 2.40nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151267BDBM151267(US8987314, B63)
Affinity DataIC50: 2.60nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151473BDBM151473(US8987314, B284)
Affinity DataIC50: 2.60nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151291BDBM151291(US8987314, B87)
Affinity DataIC50: 2.60nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151396BDBM151396(US8987314, B207)
Affinity DataIC50: 2.80nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151409BDBM151409(US8987314, B220)
Affinity DataIC50: 2.80nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151468BDBM151468(US8987314, B279)
Affinity DataIC50: 2.80nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151469BDBM151469(US8987314, B280)
Affinity DataIC50: 2.90nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 24567BDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human HL expressed in COS7 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151402BDBM151402(US8987314, B213)
Affinity DataIC50: 3nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151462BDBM151462(US8987314, B273)
Affinity DataIC50: 3nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 187287BDBM187287(US9169240, 27)
Affinity DataIC50: 3nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151404BDBM151404(US8987314, B215)
Affinity DataIC50: 3.60nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151406BDBM151406(US8987314, B217)
Affinity DataIC50: 3.60nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151422BDBM151422(US8987314, B233)
Affinity DataIC50: 3.60nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 50506506BDBM50506506(CHEMBL4465833)
Affinity DataIC50: 4nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 50506505BDBM50506505(CHEMBL4460376)
Affinity DataIC50: 4nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 187290BDBM187290(US9169240, 30)
Affinity DataIC50: 5nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151463BDBM151463(US8987314, B274)
Affinity DataIC50: 5.10nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151407BDBM151407(US8987314, B218)
Affinity DataIC50: 5.20nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 50525869BDBM50525869(CHEMBL4587475)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of hepatic lipase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151567BDBM151567(US8987314, B378)
Affinity DataIC50: 6.70nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 50522804BDBM50522804(CHEMBL4437751)
Affinity DataIC50: 7nMAssay Description:Inhibition of human hepatic lipase expressed in African green monkey COS7 cells using PED-A1 as substrate incubated for 20 mins and measured every 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151297BDBM151297(US8987314, B93)
Affinity DataIC50: 7.10nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151428BDBM151428(US8987314, B239)
Affinity DataIC50: 7.30nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151412BDBM151412(US8987314, B223)
Affinity DataIC50: 7.70nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 50506500BDBM50506500(CHEMBL4471611)
Affinity DataIC50: 9nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151442BDBM151442(US8987314, B253)
Affinity DataIC50: 9.40nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151255BDBM151255(US8987314, B51)
Affinity DataIC50: 10nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151320BDBM151320(US8987314, B118)
Affinity DataIC50: 10nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151380BDBM151380(US8987314, B185)
Affinity DataIC50: 10nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 187289BDBM187289(US9169240, 29)
Affinity DataIC50: 10nMAssay Description:Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151272BDBM151272(US8987314, B68)
Affinity DataIC50: 10nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151274BDBM151274(US8987314, B70)
Affinity DataIC50: 10nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 151331BDBM151331(US8987314, B129)
Affinity DataIC50: 10nMpH: 8.0 T: 2°CAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2015
Entry Details
US Patent

TargetHepatic triacylglycerol lipase(Human)
Bristol-Myers Squibb

US Patent
LigandChemical structure of BindingDB Monomer ID 50521233BDBM50521233(CHEMBL4458141)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human HL expressed in COS7 cells using PED-A1 containing DMPG vesicles as substrate pretreated for 20 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
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