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Report error Found 5236 for UniProtKB: P24385
TargetG1/S-specific cyclin-D1(Human)TBA
LigandPNGBDBM50519619(CHEMBL4444429)
Affinity DataKi:  0.0100nMAssay Description:Binding affinity to human BCL1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetG1/S-specific cyclin-D1(Human)TBA
LigandPNGBDBM50519624(CHEMBL4468645)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity to human BCL1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM370149(US10233188, Example 37 | US10800783, Example 37 | ...)
Affinity DataKi:  0.0600nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

TargetG1/S-specific cyclin-D1(Human)TBA
LigandPNGBDBM50514200(US10703733, Comparative Example 1 | CHEMBL4446378)
Affinity DataKi:  0.0600nMAssay Description:Binding affinity to human BCL1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetG1/S-specific cyclin-D1(Human)TBA
LigandPNGBDBM50519618(CHEMBL4465718)
Affinity DataKi:  0.0700nMAssay Description:Binding affinity to human BCL1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM370121(6-(difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcy...)
Affinity DataKi:  0.0800nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM370121(6-(difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcy...)
Affinity DataKi:  0.0800nMAssay Description:Inhibition of non-phosphorylated CDK6/Cyclin D1 (unknown origin) assessed as reduction in production of ADP using 5-FAM-RRRFRPASPLRGPPK peptide as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandPNGBDBM370162(US10233188, Example 50 | US10800783, Example 50 | ...)
Affinity DataKi:  0.0800nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandPNGBDBM462173((Scheme A-13): (3R,4R)-4-({5-chloro-4-[1-(1,1-difl...)
Affinity DataKi:  0.100nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM462174((Scheme A-14): Preparation of (3R,4R)-4-[(5-chloro...)
Affinity DataKi:  0.100nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM462081(US10766884, Example A02 | US11220494, Example A02)
Affinity DataKi:  0.100nMAssay Description:CDK4/Cyclin D1: The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM462080(US10766884, Example A01 | US11220494, Example A01)
Affinity DataKi:  0.100nMAssay Description:CDK4/Cyclin D1: The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM462208(US10766884, Example F26 | US11220494, Example F26)
Affinity DataKi:  0.100nMAssay Description:CDK4/Cyclin D1: The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM462177(US10766884, Example B01 | US11220494, Example B01)
Affinity DataKi:  0.100nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM462177(US10766884, Example B01 | US11220494, Example B01)
Affinity DataKi:  0.100nMAssay Description:CDK4/Cyclin D1: The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM462208(US10766884, Example F26 | US11220494, Example F26)
Affinity DataKi:  0.100nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM462100(US10766884, Example A17 | US11220494, Example A17)
Affinity DataKi:  0.100nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM462092(US10766884, Example A09)
Affinity DataKi:  0.100nMAssay Description:CDK4/Cyclin D1: The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM50593904(CHEMBL5198209)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
LigandPNGBDBM462229(US10766884, Example E01)
Affinity DataKi:  0.100nMAssay Description:CDK4/Cyclin D1: The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM462197(US10766884, Example F15 | US11220494, Example F15)
Affinity DataKi: <0.100nMAssay Description:CDK4/Cyclin D1: The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM533351(US11220494, Example A09)
Affinity DataKi:  0.100nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM462100(US10766884, Example A17 | US11220494, Example A17)
Affinity DataKi:  0.100nMAssay Description:CDK4/Cyclin D1: The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM462130(US10766884, Example A47 | US10766884, Example A48 ...)
Affinity DataKi:  0.100nMAssay Description:CDK4/Cyclin D1: The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM462162(US10766884, Example A78 | US11220494, Example A78)
Affinity DataKi:  0.100nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM462162(US10766884, Example A78 | US11220494, Example A78)
Affinity DataKi:  0.100nMAssay Description:CDK4/Cyclin D1: The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM462130(US10766884, Example A47 | US10766884, Example A48 ...)
Affinity DataKi:  0.100nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM462080(US10766884, Example A01 | US11220494, Example A01)
Affinity DataKi:  0.100nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM462081(US10766884, Example A02 | US11220494, Example A02)
Affinity DataKi:  0.100nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM462174((Scheme A-14): Preparation of (3R,4R)-4-[(5-chloro...)
Affinity DataKi:  0.100nMAssay Description:CDK4/Cyclin D1: The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM462173((Scheme A-13): (3R,4R)-4-({5-chloro-4-[1-(1,1-difl...)
Affinity DataKi:  0.100nMAssay Description:CDK4/Cyclin D1: The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM462108(US10766884, Example A25)
Affinity DataKi: <0.100nMAssay Description:CDK4/Cyclin D1: The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

LigandPNGBDBM462181(US10766884, Example D01 | US11220494, Example E01)
Affinity DataKi:  0.100nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM370219(US10233188, Example 109 | US10233188, Example 106 ...)
Affinity DataKi:  0.110nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandPNGBDBM370115(4-({6-(2-hydroxyethyl)-8-[(1R,2S)-2-methylcyclopen...)
Affinity DataKi:  0.120nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandPNGBDBM370147(US10233188, Example 36 | US10800783, Example 36 | ...)
Affinity DataKi:  0.130nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM467012((+)-6-(2,2-difluoroethyl)-8-[(1R*,2R*)-2-hydroxy-2...)
Affinity DataKi:  0.130nMAssay Description:Inhibition of non-phosphorylated CDK6/Cyclin D1 (unknown origin) assessed as reduction in production of ADP using 5-FAM-RRRFRPASPLRGPPK peptide as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandPNGBDBM467013((-)-6-(2,2-difluoroethyl)-8-[(1R*,2R*)-2-hydroxy-2...)
Affinity DataKi:  0.130nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandPNGBDBM370163(US10233188, Example 51 | US10800783, Example 51 | ...)
Affinity DataKi:  0.130nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandPNGBDBM370152(US10233188, Example 40 | US10800783, Example 40 | ...)
Affinity DataKi:  0.140nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandPNGBDBM370290(US10233188, Example 177 | BDBM467185)
Affinity DataKi:  0.140nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandPNGBDBM370227(US10233188, Example 114 | US10800783, Example 114 ...)
Affinity DataKi:  0.150nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandPNGBDBM370325(BDBM467220 | US10233188, Example 212)
Affinity DataKi:  0.170nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandPNGBDBM370233(US10233188, Example 120 | US10800783, Example 120 ...)
Affinity DataKi:  0.180nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandPNGBDBM370317(BDBM467212 | US10233188, Example 204)
Affinity DataKi:  0.180nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM370233(US10233188, Example 120 | US10800783, Example 120 ...)
Affinity DataKi:  0.180nMAssay Description:Inhibition of non-phosphorylated CDK6/Cyclin D1 (unknown origin) assessed as reduction in production of ADP using 5-FAM-RRRFRPASPLRGPPK peptide as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
LigandPNGBDBM370219(US10233188, Example 109 | US10233188, Example 106 ...)
Affinity DataKi:  0.190nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandPNGBDBM370256(US10233188, Example 143 | BDBM467151)
Affinity DataKi:  0.190nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandPNGBDBM462172((Scheme A-12): Preparation of (3R,4R)-4-({5-chloro...)
Affinity DataKi:  0.200nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

LigandPNGBDBM462119(US10766884, Example A36 | US11220494, Example A36)
Affinity DataKi:  0.200nMAssay Description:CDK4/Cyclin D1: The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2021
Entry Details
US Patent

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