Compile Data Set for Download or QSAR
Report error Found 1049 of affinity data for UniProtKB/TrEMBL: P25021
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127601(2-(1H-Imidazol-4-yl)-cyclopropylamine | CHEMBL5938...)
Affinity DataEC50: >0.000100nMAssay Description:Inhibition of human Histamine H2 receptor using [3H]tiotidineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127604(C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine |...)
Affinity DataEC50: >0.000100nMAssay Description:Inhibition of human Histamine H2 receptor using [3H]tiotidineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127603(C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine |...)
Affinity DataEC50: >0.000100nMAssay Description:Inhibition of human Histamine H2 receptor using [3H]tiotidineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127602(C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine |...)
Affinity DataEC50: >0.000100nMAssay Description:Inhibition of human Histamine H2 receptor using [3H]tiotidineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127609(C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine |...)
Affinity DataEC50: >0.000100nMAssay Description:Inhibition of human Histamine H2 receptor using [3H]tiotidineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127606(2-(1H-Imidazol-4-yl)-cyclopropylamine | CHEMBL2940...)
Affinity DataEC50: >0.000100nMAssay Description:Inhibition of human Histamine H2 receptor using [3H]tiotidineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50127610((1S,2S)-2-(2-aminoethyl)-1-(1H-imidazol-4-yl)cyclo...)
Affinity DataEC50: >0.000100nMAssay Description:Inhibition of human Histamine H2 receptor using [3H]tiotidineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50172414(2-(2,4-Dichloro-phenoxy)-N-[2-(2-dimethylamino-eth...)
Affinity DataIC50: 0.870nMAssay Description:Inhibitory concentration against histamine H2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50253754(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N-m...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]tiotidine from human histamine H2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50568741(CHEMBL4875600)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor expressed in sf9 insect cell membranes co-expressing GSalphaS incubated for 60 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50609113(CHEMBL5276441)
Affinity DataKi:  2nMAssay Description:Antagonist activity at histamine H2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601551(CHEMBL5207281)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601567(CHEMBL5206565)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at human histamine H2 receptor stably expressed in HEK293T cells co-expressing NlucN-mGs/hH2R-NlucC assessed as induction of mini-Gi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50568740(CHEMBL4860528)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor expressed in sf9 insect cell membranes co-expressing GSalphaS incubated for 60 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50315205((R)-2-(6-fluoro-3-(1-(3-methoxypyrazin-2-yl)ethyl)...)
Affinity DataKi:  4.5nMAssay Description:Inhibition of H2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601590(CHEMBL5173079)
Affinity DataKi:  4.80nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601568(CHEMBL5178472)
Affinity DataEC50:  4.90nMAssay Description:Agonist activity at human histamine H2 receptor stably expressed in HEK293T cells co-expressing NlucN-mGs/hH2R-NlucC assessed as induction of mini-Gi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601567(CHEMBL5206565)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601556(CHEMBL5200771)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601589(CHEMBL5176229)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50445613(CHEBI:71246 | Asenapine maleate | Saphris | ORG-52...)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]Cimetidine from histamine H2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601551(CHEMBL5207281)
Affinity DataEC50:  5.80nMAssay Description:Agonist activity at human histamine H2 receptor stably expressed in HEK293T cells co-expressing NlucN-mGs/hH2R-NlucC assessed as induction of mini-Gi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50445613(CHEBI:71246 | Asenapine maleate | Saphris | ORG-52...)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]Cimetidine from histamine H2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601556(CHEMBL5200771)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human histamine H2 receptor stably expressed in HEK293T cells co-expressing NlucN-mGs/hH2R-NlucC assessed as induction of mini-Gi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601552(CHEMBL5183205)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human histamine H2 receptor stably expressed in HEK293T cells co-expressing NlucN-mGs/hH2R-NlucC assessed as induction of mini-Gi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50394694(CHEMBL2165642)
Affinity DataEC50:  6.17nMAssay Description:Agonist activity at human H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601572(CHEMBL5208722)
Affinity DataKi:  6.20nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50415915(CHEMBL1096431)
Affinity DataEC50:  6.46nMAssay Description:Agonist activity at GsalphaS-fused human histamine H2 receptor expressed in Sf9 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601577(CHEMBL5180504)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50586673(CHEMBL5092102)
Affinity DataEC50:  7.40nMAssay Description:Agonist activity at human H2 receptor expressed in HEK293T-ARRB2 cells assessed as stimulation of beta-arrestin 2 recruitmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50394703(CHEMBL2165628)
Affinity DataEC50:  7.59nMAssay Description:Agonist activity at human H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50586674(CHEMBL5094083)
Affinity DataEC50:  7.60nMAssay Description:Agonist activity at human H2 receptor expressed in HEK293T-ARRB2 cells assessed as stimulation of beta-arrestin 2 recruitmentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50394698(CHEMBL2165632)
Affinity DataEC50:  7.76nMAssay Description:Agonist activity at human H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601576(CHEMBL5184911)
Affinity DataEC50:  8.10nMAssay Description:Agonist activity at human histamine H2 receptor stably expressed in HEK293T cells co-expressing NlucN-mGs/hH2R-NlucC assessed as induction of mini-Gi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601576(CHEMBL5184911)
Affinity DataKi:  8.10nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50415919(CHEMBL1094144)
Affinity DataEC50:  9.33nMAssay Description:Agonist activity at GsalphaS-fused human histamine H2 receptor expressed in Sf9 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50568759(CHEMBL4865965)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor expressed in sf9 insect cell membranes co-expressing GSalphaS incubated for 60 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601563(CHEMBL5204599)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human histamine H2 receptor stably expressed in HEK293T cells co-expressing NlucN-mGs/hH2R-NlucC assessed as induction of mini-Gi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50116766((6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiaz...)
Affinity DataKd:  12nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50121205(CHEBI:18295 | Histamine)
Affinity DataKd:  12nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601552(CHEMBL5183205)
Affinity DataKd:  12nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601551(CHEMBL5207281)
Affinity DataKd:  12nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601554(CHEMBL5204739)
Affinity DataKd:  12nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601553(CHEMBL5209081)
Affinity DataKd:  12nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601588(CHEMBL5174278)
Affinity DataKd:  12nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601587(CHEMBL5172675)
Affinity DataKd:  12nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601590(CHEMBL5173079)
Affinity DataKd:  12nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601589(CHEMBL5176229)
Affinity DataKd:  12nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601591(CHEMBL5187758)
Affinity DataKd:  12nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistamine H2 receptor(Human)
Hokkaido University

Curated by ChEMBL
LigandPNGBDBM50601572(CHEMBL5208722)
Affinity DataKd:  12nMAssay Description:Displacement of [3H]UR-DE257 from human histamine H2 receptor stably expressed in baculovirus infected Sf9 cell membrane co-expressing RG-Salpha S in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
Displayed 1 to 50 (of 1049 total ) | Next | Last >>
Jump to: