Compile Data Set for Download or QSAR
Report error Found 33 of affinity data for UniProtKB/TrEMBL: Q2M1Q3
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324346BDBM50324346(Cyclohexyl-[6-piperazin-1-yl-4-(1H-pyrazol-4-yl)[2...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324324BDBM50324324(2'-Phenylamino-6-piperazin-1-yl[2,4']bipyridinyl-4...)
Affinity DataIC50: 1nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324348BDBM50324348(6-(piperazin-1-yl)-4-(4H-pyrazol-4-yl)-N-(tetrahyd...)
Affinity DataIC50: 2nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324347BDBM50324347(Isopropyl-[6-piperazin-1-yl-4-(1H-pyrazol-4-yl)[2,...)
Affinity DataIC50: 2nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324327BDBM50324327(2'-(1-Methyl-1H-pyrazol-3-ylamino)-6-piperazin-1-y...)
Affinity DataIC50: 7nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324328BDBM50324328(2'-(2-Chlorophenylamino)-6-piperazin-1-yl[2,4']bip...)
Affinity DataIC50: 8nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324326BDBM50324326(4'-tert-Butylcarbamoyl-2''-isopropylamino-3,4,5,6-...)
Affinity DataIC50: 8nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324325BDBM50324325(6-Piperazin-1-yl-2'-(tetrahydropyran-4-ylamino)[2,...)
Affinity DataIC50: 9nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324323BDBM50324323(2'-Cyclohexylamino-6-piperazin-1-yl[2,4']bipyridin...)
Affinity DataIC50: 9nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324335BDBM50324335(2'-Cyclohexylamino-6-((R)-pyrrolidin-3-ylamino)[2,...)
Affinity DataIC50: 18nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324330BDBM50324330(2'-Ethylamino-6-piperazin-1-yl[2,4']bipyridinyl-4-...)
Affinity DataIC50: 31nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324332BDBM50324332(2'-Phenylamino-6-piperazin-1-yl[2,4']bipyridinyl-4...)
Affinity DataIC50: 35nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50336958BDBM50336958(2-Methoxy-7H,8H,9H-1,4-thiazepino[7',6'-5,4]thioph...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant PKD2 after 10 mins by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324329BDBM50324329(2'-Cyclopentylamino-6-piperazin-1-yl[2,4']bipyridi...)
Affinity DataIC50: 59nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324337BDBM50324337(2'-Cyclohexylamino-6-((R)-3-methylpiperazin-1-yl)[...)
Affinity DataIC50: 60nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324334BDBM50324334(Cyclohexyl-[6-piperazin-1-yl-4-(2H-pyrazol-3-yl)[2...)
Affinity DataIC50: 62nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324333BDBM50324333(2'-(1-Methyl-1H-pyrazol-3-ylamino)-6-piperazin-1-y...)
Affinity DataIC50: 68nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324345BDBM50324345(Cyclohexyl-(4-difluoromethyl-6-piperazin-1-yl[2,4'...)
Affinity DataIC50: 76nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324338BDBM50324338(2'-Cyclohexylamino-6-((S)-3-methylpiperazin-1-yl)[...)
Affinity DataIC50: 86nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324344BDBM50324344(Cyclohexyl-(6-piperazin-1-yl-4-trifluoromethyl[2,4...)
Affinity DataIC50: 101nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324331BDBM50324331(2'-Cyclohexylamino-6-piperazin-1-yl[2,4']bipyridin...)
Affinity DataIC50: 130nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324339BDBM50324339(3-Amino-2''-cyclohexylamino-3,4,5,6-tetrahydro-2H-...)
Affinity DataIC50: 168nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402020BDBM50402020(CHEMBL2205426)
Affinity DataKi:  175nMAssay Description:Inhibition of recombinant PKD2 after 1 hr by scintillation counter analysis in presence of gamma-[33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324341BDBM50324341(Aminomethyl-2''-cyclohexylamino-3,4,5,6-tetrahydro...)
Affinity DataIC50: 212nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324340BDBM50324340(2'-Cyclohexylamino-6-(4-methylpiperazin-1-yl)[2,4'...)
Affinity DataIC50: 238nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 32334BDBM32334(7-hydroxy-2,3,4,5-tetrahydro-[1]benzofuro[2,3-c]az...)
Affinity DataIC50: 280nMAssay Description:Inhibition of human recombinant PKD2 after 10 mins by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324342BDBM50324342(2'-Cyclohexylamino-6-(3,3-dimethylpiperazin-1-yl)[...)
Affinity DataIC50: 427nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50324336BDBM50324336(2'-Cyclohexylamino-6-((S)-pyrrolidin-3-ylamino)[2,...)
Affinity DataIC50: 540nMAssay Description:Inhibition of PKD2 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 910nMAssay Description:Inhibition of PKD2 (unknown origin) by ADP-Glo Kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50123803BDBM50123803(CHEMBL3623375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PKD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2016
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13533BDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PKD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359359BDBM50359359(CHEMBL1929238)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PKD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetPolycystin-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639412BDBM50639412(CHEMBL5562073)
Affinity DataIC50: 4.03E+4nMAssay Description:Inhibition of PKD2 (unknown origin) by ADP-Glo Kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed