Compile Data Set for Download or QSAR
Report error Found 15 for UniProtKB: Q6PAJ1
TargetBreakpoint cluster region protein(Mouse)
Oregon Health and Science University Cancer Institute

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of WT BCR-ABL (unknown origin) expressed in mouse BaF3 cells assessed as inhibition of cell growth incubated for 72 hrs by methane-thiosul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBreakpoint cluster region protein(Mouse)
Oregon Health and Science University Cancer Institute

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 10nMAssay Description:Inhibition of WT BCR-ABL (unknown origin) expressed in mouse BaF3 cells assessed as inhibition of tyrosine phosphorylation incubated for 3 hrs by imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBreakpoint cluster region protein(Mouse)
Oregon Health and Science University Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50237710(AMN 107 | AMN107 | 4-methyl-N-[3-(4-methyl-1H-imid...)
Affinity DataIC50: 10nMAssay Description:Inhibition of WT BCR-ABL (unknown origin) expressed in mouse BaF3 cells assessed as inhibition of tyrosine phosphorylation incubated for 3 hrs by imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBreakpoint cluster region protein(Mouse)
Oregon Health and Science University Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50237710(AMN 107 | AMN107 | 4-methyl-N-[3-(4-methyl-1H-imid...)
Affinity DataIC50: 13nMAssay Description:Inhibition of WT BCR-ABL (unknown origin) expressed in mouse BaF3 cells assessed as inhibition of cell growth incubated for 72 hrs by methane-thiosul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBreakpoint cluster region protein(Mouse)
Oregon Health and Science University Cancer Institute

Curated by ChEMBL
LigandPNGBDBM185674(Rebastinib | 4-[4-[(5-tert-butyl-2-quinolin-6-ylpy...)
Affinity DataIC50: 18nMAssay Description:Inhibition of native BCR-ABL T315I mutant autophosphorylation in mouse BaF3 cells incubated for 6 hrs by immunoblot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBreakpoint cluster region protein(Mouse)
Oregon Health and Science University Cancer Institute

Curated by ChEMBL
LigandPNGBDBM185674(Rebastinib | 4-[4-[(5-tert-butyl-2-quinolin-6-ylpy...)
Affinity DataIC50: 29nMAssay Description:Inhibition of native BCR-ABL autophosphorylation in mouse BaF3 cells incubated for 6 hrs by immunoblot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBreakpoint cluster region protein(Mouse)
Oregon Health and Science University Cancer Institute

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 38nMAssay Description:Inhibition of Bcr-Abl phosphorylation in BALB/c mouse 3T3 by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBreakpoint cluster region protein(Mouse)
Oregon Health and Science University Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50290422(4-(4-Methyl-piperazin-1-ylmethyl)-N-[3-(4-pyridin-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Bcr-Abl phosphorylation in BALB/c mouse 3T3 by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBCR/ABL1(Mouse)
Hangzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50590370(Vodobatinib | K-0706 | K0706 | Sco-088 | VODOBATIN...)
Affinity DataIC50: 165nMAssay Description:Inhibition of BCR-ABL E255V mutant phosphorylation in mouse BaF3 cells incubated for 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetBreakpoint cluster region protein(Mouse)
Oregon Health and Science University Cancer Institute

Curated by ChEMBL
LigandPNGBDBM86734(CAS_220127-57-1 | NSC_0 | Gleevec)
Affinity DataIC50: 260nMAssay Description:Inhibition of WT BCR-ABL (unknown origin) expressed in mouse BaF3 cells assessed as inhibition of cell growth incubated for 72 hrs by methane-thiosul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBreakpoint cluster region protein(Mouse)
Oregon Health and Science University Cancer Institute

Curated by ChEMBL
LigandPNGBDBM86734(CAS_220127-57-1 | NSC_0 | Gleevec)
Affinity DataIC50: 280nMAssay Description:Inhibition of WT BCR-ABL (unknown origin) expressed in mouse BaF3 cells assessed as inhibition of tyrosine phosphorylation incubated for 3 hrs by imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBreakpoint cluster region protein(Mouse)
Oregon Health and Science University Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50590370(Vodobatinib | K-0706 | K0706 | Sco-088 | VODOBATIN...)
Affinity DataIC50: 1.97E+3nMAssay Description:Inhibition of BCR-ABL T315I mutant phosphorylation in mouse BaF3 cells incubated for 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetBreakpoint cluster region protein(Mouse)
Oregon Health and Science University Cancer Institute

Curated by ChEMBL
LigandPNGBDBM86734(CAS_220127-57-1 | NSC_0 | Gleevec)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of native BCR-ABL T315I mutant autophosphorylation in mouse BaF3 cells incubated for 6 hrs by immunoblot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBreakpoint cluster region protein(Mouse)
Oregon Health and Science University Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50237710(AMN 107 | AMN107 | 4-methyl-N-[3-(4-methyl-1H-imid...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of native BCR-ABL T315I mutant autophosphorylation in mouse BaF3 cells incubated for 6 hrs by immunoblot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBreakpoint cluster region protein(Mouse)
Oregon Health and Science University Cancer Institute

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of native BCR-ABL T315I mutant autophosphorylation in mouse BaF3 cells incubated for 6 hrs by immunoblot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed