Compile Data Set for Download or QSAR
Report error Found 330 of affinity data for UniProtKB/TrEMBL: Q8NFS2
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614234BDBM50614234(CHEMBL5285249)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human mGluR7 expressed in CHO cells expressing CRE-Luc reporter gene assessed as reduction in forskolin-stimulated cAMP productio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614232BDBM50614232(CHEMBL5266235)
Affinity DataEC50:  7nMAssay Description:Agonist activity at human mGluR7 expressed in CHO cells expressing CRE-Luc reporter gene assessed as reduction in forskolin-stimulated cAMP productio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614233BDBM50614233(CHEMBL5280256)
Affinity DataEC50:  28nMAssay Description:Agonist activity at human mGluR7 expressed in CHO cells expressing CRE-Luc reporter gene assessed as reduction in forskolin-stimulated cAMP productio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614231BDBM50614231(CHEMBL5288955)
Affinity DataEC50:  38nMAssay Description:Agonist activity at human mGluR7 expressed in CHO cells expressing CRE-Luc reporter gene assessed as reduction in forskolin-stimulated cAMP productio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614235BDBM50614235(CHEMBL5286456)
Affinity DataEC50:  55nMAssay Description:Agonist activity at human mGluR7 expressed in CHO cells expressing CRE-Luc reporter gene assessed as reduction in forskolin-stimulated cAMP productio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 58360BDBM58360(MLS001173561 | N,N'-dibenzhydrylethane-1,2-diamine...)
Affinity DataEC50:  64nMAssay Description:Agonist activity at human mGluR7b expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552347BDBM50552347(CHEMBL4798021)
Affinity DataEC50:  98nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552346BDBM50552346(CHEMBL4777502)
Affinity DataEC50:  106nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614239BDBM50614239(CHEMBL5272418)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human mGluR7b expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614236BDBM50614236(CHEMBL5291195)
Affinity DataEC50:  113nMAssay Description:Agonist activity at human mGluR7 expressed in CHO cells expressing CRE-Luc reporter gene assessed as reduction in forskolin-stimulated cAMP productio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552348BDBM50552348(CHEMBL4764083)
Affinity DataEC50:  114nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50283487BDBM50283487(CHEMBL4162576)
Affinity DataEC50:  148nMAssay Description:Positive allosteric modulation of mGluR7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614238BDBM50614238(CHEMBL5281755)
Affinity DataEC50:  156nMAssay Description:Agonist activity at human mGluR7 expressed in CHO cells expressing CRE-Luc reporter gene assessed as reduction in forskolin-stimulated cAMP productio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552330BDBM50552330(CHEMBL4745982)
Affinity DataEC50:  180nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552342BDBM50552342(CHEMBL4787053)
Affinity DataEC50:  201nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552354BDBM50552354(CHEMBL4799902)
Affinity DataEC50:  302nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552349BDBM50552349(CHEMBL4792152)
Affinity DataEC50:  372nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552333BDBM50552333(CHEMBL4760570)
Affinity DataEC50:  377nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552332BDBM50552332(CHEMBL4797971)
Affinity DataEC50:  400nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50552343BDBM50552343(CHEMBL4746530)
Affinity DataEC50:  487nMAssay Description:Positive allosteric modulation of human mGluR7 in presence of EC20 concentration of L-AP4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564961BDBM564961(US11414395, Example 8)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564962BDBM564962(US11414395, Example 9)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564959BDBM564959(US11414395, Example 6)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564960BDBM564960(US11414395, Example 7)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564965BDBM564965(US11414395, Example 12)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564966BDBM564966(US11414395, Example 13)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564963BDBM564963(US11414395, Example 10)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564964BDBM564964(US11414395, Example 11)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564969BDBM564969(US11414395, Example 16)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564970BDBM564970(US11414395, Example 17)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564967BDBM564967(US11414395, Example 14)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564968BDBM564968(US11414395, Example 15)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564973BDBM564973(US11414395, Example 20)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564974BDBM564974(US11414395, Example 21)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564971BDBM564971(US11414395, Example 18)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564972BDBM564972(US11414395, Example 19)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564954BDBM564954(US11414395, Example 1)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564958BDBM564958(US11414395, Example 5)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564993BDBM564993(US11414395, Example 41)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564994BDBM564994(US11414395, Example 42)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564991BDBM564991(US11414395, Example 39)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564992BDBM564992(US11414395, Example 40)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564997BDBM564997(US11414395, Example 45)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564998BDBM564998(US11414395, Example 46)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564995BDBM564995(US11414395, Example 43)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564996BDBM564996(US11414395, Example 44)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 565001BDBM565001(US11414395, Example 49)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 565002BDBM565002(US11414395, Example 50)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 564999BDBM564999(US11414395, Example 47)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetMetabotropic glutamate receptor 7(Human)
Cerevance

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 565005BDBM565005(US11414395, Example 53)
Affinity DataIC50: 500nMAssay Description:The HTRF-based assays from CisBio Bioassays allow the measure of different cell signaling pathways, notably those allowing the determination of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

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