Compile Data Set for Download or QSAR
Report error Found 98 of affinity data for UniProtKB/TrEMBL: Q91ZY2
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509072(CHEMBL4454158)
Affinity DataEC50:  0.251nMAssay Description:Agonist activity at mouse H4R expressed in HEK293-SF-mH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509065(CHEMBL4439142)
Affinity DataEC50:  1nMAssay Description:Agonist activity at mouse H4R expressed in HEK293-SF-mH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50514105(CHEMBL4441731)
Affinity DataEC50:  1nMAssay Description:Agonist activity at mouse H4R expressed on HEK293T cells assessed as inhibition of forskolin-induced CRE-driven luciferase activity co-incubated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509078(CHEMBL4443126)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at mouse H4R expressed in HEK293-SF-mH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538682(CHEMBL4597218)
Affinity DataKi:  1.20nMAssay Description:Inhibition of UR-DEBa242 binding to mouse recombinant NLuc/GPCR-fused H4R expressed in HEK293T cells measured after 30 mins by furimazine substrate b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataKi:  3.89nMAssay Description:Displacement of [3H]-histamine from mouse H4R expressed in HEK293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509071(CHEMBL4455324)
Affinity DataEC50:  4.20nMAssay Description:Agonist activity at mouse H4R expressed in HEK293-SF-mH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataKi:  4.60nM ΔG°:  -47.6kJ/molepH: 7.5 T: 2°CAssay Description:The Ki values were calculated based on an experimentally determined appropriate Kd value according to Cheng and Prusoff.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2008
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50006789(CHEMBL3236549)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]histamine from mouse recombinant histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50006789(CHEMBL3236549)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]histamine from mouse histamine H4 receptor expressed in SK-N-MC cells after 45 mins by competition binding analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509064(CHEMBL4445423)
Affinity DataEC50:  6.20nMAssay Description:Agonist activity at mouse H4R expressed in HEK293-SF-mH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50006742(CHEMBL3236553)
Affinity DataEC50:  7.30nMAssay Description:Partial agonist activity at mouse histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50483137(CHEMBL1632413)
Affinity DataKi:  7.90nMAssay Description:Binding affinity to mouse histamine H4 receptor expressed in human SK-N-MC cells by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50483138(CHEMBL1632414)
Affinity DataKi:  7.90nMAssay Description:Binding affinity to mouse histamine H4 receptor expressed in human SK-N-MC cells by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50483137(CHEMBL1632413)
Affinity DataEC50:  10nMAssay Description:Agonist activity at mouse histamine H4 receptor by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509072(CHEMBL4454158)
Affinity DataEC50:  11nMAssay Description:Agonist activity at mouse H4R expressed in HEK293T-beta-arr2-mH4R cells by beta-arrestin2 recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataKi:  12nMAssay Description:Inhibition of UR-DEBa242 binding to mouse recombinant NLuc/GPCR-fused H4R expressed in HEK293T cells measured after 30 mins by furimazine substrate b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50319302(5-(3-(4-(5-fluoro-4-methyl-1H-benzo[d]imidazol-2-y...)
Affinity DataEC50:  12nMAssay Description:Displacement of [3H]histamine from mouse recombinant histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538682(CHEMBL4597218)
Affinity DataEC50:  13nMAssay Description:Agonist activity at mouse recombinant H4R expressed in HEK293T cells by beta-arrestin recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50433359(CHEMBL2376804)
Affinity DataKi:  15nMAssay Description:Binding affinity to mouse histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509068(CHEMBL4515149)
Affinity DataKd:  15nMAssay Description:Binding affinity to mouse H4R expressed in HEK293T-SF-His6-CRE-Luc cells by saturation binding studyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50514105(CHEMBL4441731)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]histamine from mouse H4R expressed in HEK293T cells incubated for 2 hrs by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509068(CHEMBL4515149)
Affinity DataKd:  17nMAssay Description:Binding affinity to mouse H4R expressed in HEK293T-SF-His6-CRE-Luc cells assessed as equilibrium dissociation constant by saturation binding studyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50483139(CHEMBL1632412)
Affinity DataKi:  20nMAssay Description:Binding affinity to mouse histamine H4 receptor expressed in human SK-N-MC cells by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50433358(CHEMBL2376803)
Affinity DataKi:  20nMAssay Description:Binding affinity to mouse histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50006742(CHEMBL3236553)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]histamine from mouse histamine H4 receptor expressed in SK-N-MC cells after 45 mins by competition binding analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50356884(CHEMBL1915540)
Affinity DataKi:  20.9nMAssay Description:Displacement of [3H]-histamine from mouse H4R expressed in HEK293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50356884(CHEMBL1915540)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]histamine from mouse histamine H4 receptor expressed in HEK293T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50361012(CHEMBL1935574)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]histamine from mouse H4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509078(CHEMBL4443126)
Affinity DataEC50:  26nMAssay Description:Agonist activity at mouse H4R expressed in HEK293T-beta-arr2-mH4R cells by beta-arrestin2 recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)
Affinity DataEC50:  28nMAssay Description:Antagonist activity at mouse H4R expressed in HEK293 cells co-expressing ELucC/ELucN-beta-arrestin2 assessed as inhibition of histamine-induced beta-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538677(CHEMBL4635634)
Affinity DataKd:  31nMAssay Description:Binding affinity to mouse recombinant NLuc/GPCR-fused H4R expressed in HEK293T cells assessed as dissociation constant measured after 30 mins in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538681(CHEMBL4595327)
Affinity DataKi:  31nMAssay Description:Inhibition of UR-DEBa242 binding to mouse recombinant NLuc/GPCR-fused H4R expressed in HEK293T cells measured after 30 mins by furimazine substrate b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538677(CHEMBL4635634)
Affinity DataKd:  31.2nMAssay Description:Binding affinity to mouse recombinant NLuc/GPCR-fused H4R expressed in HEK293T cells assessed as dissociation constant measured after 30 mins in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509068(CHEMBL4515149)
Affinity DataKd:  34nMAssay Description:Binding affinity to mouse H4R expressed in HEK293T-SF-His6-CRE-Luc cells assessed as kinetically derived dissociation constant by saturation binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509068(CHEMBL4515149)
Affinity DataKd:  34nMAssay Description:Binding affinity to mouse H4R expressed in HEK293T-SF-His6-CRE-Luc cells by kinetic binding studyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509074(CHEMBL4543119)
Affinity DataEC50:  35nMAssay Description:Agonist activity at mouse H4R expressed in HEK293-SF-mH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50319300(N-(2-(1H-imidazol-4-yl)ethyl)-3-(4-(5-fluoro-4-met...)
Affinity DataEC50:  39nMAssay Description:Intrinsic activity at mouse histamine H4 receptor expressed in human SK-N-MC cells assessed as inhibition of forskolin-induced cAMP responsive elemen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataIC50: 40nMAssay Description:Inhibition of histamine H4 receptor-mediated chemotaxis in mouse bone marrow cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50121205(CHEBI:18295 | Histamine)
Affinity DataKd:  42nMAssay Description:Binding affinity to mouse H4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50121205(CHEBI:18295 | Histamine)
Affinity DataKi:  42nMAssay Description:Binding affinity to mouse histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50433357(CHEMBL2376800)
Affinity DataKi:  50nMAssay Description:Binding affinity to mouse histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538681(CHEMBL4595327)
Affinity DataEC50:  50nMAssay Description:Agonist activity at mouse recombinant H4R expressed in HEK293T cells by beta-arrestin recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538677(CHEMBL4635634)
Affinity DataEC50:  50nMAssay Description:Antagonist activity at mouse H4R expressed in HEK293 cells co-expressing ELucC/ELucN-beta-arrestin2 assessed as inhibition of histamine-induced beta-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509067(CHEMBL4518374)
Affinity DataEC50:  51nMAssay Description:Agonist activity at mouse H4R expressed in HEK293-SF-mH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509065(CHEMBL4439142)
Affinity DataEC50:  51nMAssay Description:Agonist activity at mouse H4R expressed in HEK293T-beta-arr2-mH4R cells by beta-arrestin2 recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50509075(CHEMBL4437371)
Affinity DataEC50:  51nMAssay Description:Agonist activity at mouse H4R expressed in HEK293-SF-mH4R-His6-CRE-Luc cells incubated for 5 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538677(CHEMBL4635634)
Affinity DataKd:  52nMAssay Description:Binding affinity to recombinant mouse N- terminal NLuc-tagged H4R expressed in HEK293T cells by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50538677(CHEMBL4635634)
Affinity DataKd:  52.2nMAssay Description:Binding affinity to recombinant mouse N- terminal NLuc-tagged H4R expressed in HEK293T cells by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50356884(CHEMBL1915540)
Affinity DataKi:  55nMAssay Description:Binding affinity to mouse histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
Displayed 1 to 50 (of 98 total ) | Next | Last >>
Jump to: