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Report error Found 32 of affinity data for UniProtKB/TrEMBL: Q9H9Z5
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619701BDBM50619701(CHEMBL1575436)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054344BDBM50054344(US9522881, 11a-1 L97M74 | CHEMBL3319356 | US984453...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of MKP5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50054344BDBM50054344(US9522881, 11a-1 L97M74 | CHEMBL3319356 | US984453...)
Affinity DataIC50: 2.90E+3nMAssay Description:For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
US Patent

TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619701BDBM50619701(CHEMBL1575436)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human MKP5 catalytic domain (320 to 467 residues) expressed in Escherichia coli BL21 (DE3) cells by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619703BDBM50619703(CHEMBL5418996)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619709BDBM50619709(CHEMBL5393799)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087856BDBM50087856(CHEMBL3426913)
Affinity DataIC50: 5.70E+3nMpH: 7.0Assay Description:Inhibition of MKP5 (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619702BDBM50619702(CHEMBL5420188)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250606BDBM50250606(CHEMBL4077342)
Affinity DataKi:  6.90E+3nMAssay Description:Inhibition of MKP5 (unknown origin) using pNPP as substrate preincubated for 5 mins followed by substrate addition measured for 20 mins by spectropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2019
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619710BDBM50619710(CHEMBL5427332)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619704BDBM50619704(CHEMBL5396788)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619707BDBM50619707(CHEMBL5428133)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619711BDBM50619711(CHEMBL5434976)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619712BDBM50619712(CHEMBL5416499)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619719BDBM50619719(CHEMBL5427448)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50544440BDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MKP5 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50544431BDBM50544431(CHEMBL4637459 | US11192850, Entry 4k)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MKP5 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50544427BDBM50544427(CHEMBL4632818 | US11192850, Entry 4g)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of MKP5 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619721BDBM50619721(CHEMBL5399164)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619705BDBM50619705(CHEMBL5418920)
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619715BDBM50619715(CHEMBL5405382)
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619720BDBM50619720(CHEMBL5405398)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50441298BDBM50441298(CHEMBL2431708)
Affinity DataKi:  1.50E+5nMAssay Description:Inhibition of human MKP5 using DiFMUP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619718BDBM50619718(CHEMBL5419280)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619706BDBM50619706(CHEMBL5419382)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619708BDBM50619708(CHEMBL5405183)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619713BDBM50619713(CHEMBL5404337)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619714BDBM50619714(CHEMBL5420697)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619717BDBM50619717(CHEMBL5397402)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619716BDBM50619716(CHEMBL5434241)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of MKP5 catalytic domain (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as p38alpha MAPK phosphopeptide dephosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50441297BDBM50441297(CHEMBL2431666 | CHEMBL2431664)
Affinity DataKi:  3.40E+5nMAssay Description:Inhibition of human MKP5 using DiFMUP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 10(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50441296BDBM50441296(CHEMBL2431667 | CHEMBL2431665)
Affinity DataKi: >5.00E+5nMAssay Description:Inhibition of human MKP5 using DiFMUP as substrate after 5 mins by spectrophotometric plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed