Affinity DataKi: 37nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from rat liverMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from rat liverMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from rat liverMore data for this Ligand-Target Pair
Affinity DataKi: 4.40E+3nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
Affinity DataKi: 4.50E+3nMAssay Description:Compound was tested for kinetic inhibition constant against Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
Affinity DataKi: 6.00E+4nMAssay Description:Inhibition constant against rat liver Oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from Candida albicansMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Antibacterial activity of TMP-susceptible Dihydrofolate reductase against Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from Candida albicansMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antibacterial activity of TMP-susceptible Dihydrofolate reductase against Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antibacterial activity of TMP-susceptible Dihydrofolate reductase against Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Antibacterial activity of TMP-susceptible Dihydrofolate reductase against Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Antibacterial activity of the compound against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 9.80nMAssay Description:Antibacterial activity of the compound against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Antibacterial activity of the compound against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory activity of TMP-susceptible Dihydrofolate reductase against Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Antibacterial activity of the compound against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Antibacterial activity of the compound against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Antibacterial activity of the compound against TMP-Resistant Dihydrofolate reductase from Staphylococcus aureus 157/4696More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Staphylococcus aureus (strain MW2))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibitory activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus aureus 157/4696More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Antibacterial activity of the compound against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Staphylococcus aureus (strain MW2))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibitory activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus aureus 157/4696More data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibitory activity of the compound against TMP-susceptible DHFR from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Antibacterial activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus pneumoniae 1/1More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition against rat liver Oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibitory activity of TMP-susceptible Dihydrofolate reductase against Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibitory activity of TMP-Resistance DHFR against Staphylococcus pneumoniae 1/1More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Antibacterial activity of TMP-susceptible Dihydrofolate reductase against Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Antibacterial activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus pneumoniae 1/1More data for this Ligand-Target Pair
Affinity DataIC50: 540nMAssay Description:Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from Candida albicansMore data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inhibitory activity against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair
Affinity DataIC50: 670nMAssay Description:Antibacterial activity against TMP-Resistance Dihydrofolate reductase from Staphylococcus pneumoniae 1/1More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for inhibition of purified Oxidosqualene-lanosterol cyclase from pig liverMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Antibacterial activity of the compound against TMP-susceptible Dihydrofolate reductase from Staphylococcus pneumoniae ATCC 49619More data for this Ligand-Target Pair