Affinity DataKi: 0.0250nMAssay Description:Inhibition constant against human cathepsin L using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 0.0360nMAssay Description:Inhibition constant against human cathepsin L using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 0.0400nM ΔG°: -14.0kcal/molepH: 5.5 T: 2°CAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
Affinity DataKi: 0.0450nMAssay Description:Inhibition of human recombinant cathepsin L after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0680nM ΔG°: -13.7kcal/molepH: 5.5 T: 2°CAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substrate addition by fluor...More data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibition of human recombinant cathepsin L after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Inhibition of human recombinant cathepsin L after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Inhibition of human recombinant cathepsin L after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Inhibition of human recombinant cathepsin L after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of human cathepsin L using Cbz-Phe-Arg-AMC as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of human recombinant cathepsin L after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 0.470nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Inhibitory activity of the compound against Human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substrate addition by fluor...More data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Ability to block cathepsin L-catalyzed hydrolysis of the fluorogenic substrate Z-Phe-Arg-NHMecMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of human Cathepsin L assessed as inhibition constant using Cbz-Phe-Arg-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.610nMAssay Description:Inhibition of human cathepsin L using Cbz-Phe-Arg-AMC as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.630nM ΔG°: -12.4kcal/molepH: 5.5 T: 2°CAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 0.790nMAssay Description:Inhibition constant against human cathepsin L using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
Affinity DataKi: 0.870nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition of human recombinant cathepsin L after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibitory activity against recombinant human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibitory activity against recombinant human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibitory activity against recombinant human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibitory activity against recombinant human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of human recombinant cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of human recombinant cathepsin L after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition of human CatL using Cbz-Phe-Arg-AMC as substrate measured over 30 mins by fluorimetric methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by substrate addition by fluor...More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of human liver cathepsin L using Cbz-Phe-Arg-pNA as substrate incubated for 30 mins measured for 20 mins by photometrical analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibitory activity against recombinant human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of human recombinant cathepsin L after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibitory activity of the compound against human Cathepsin LMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of human recombinant cathepsin L after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Inhibition of human Cathepsin L assessed as inhibition constant using Cbz-Phe-Arg-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Apparent inhibitory constant against human cathepsin LMore data for this Ligand-Target Pair